BDBM50054076 7-Dimethylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::CHEMBL135932

SMILES: CN(C)C1CCc2ccc(O)cc2C1

InChI Key: InChIKey=YVQFTRVYMAREIA-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50054076   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50054076 (7-Dimethylamino-5,6,7,8-tetrahydro-naphthalen-2-ol...) Show SMILES CN(C)C1CCc2ccc(O)cc2C1 Show InChI InChI=1S/C12H17NO/c1-13(2)11-5-3-9-4-6-12(14)8-10(9)7-11/h4,6,8,11,14H,3,5,7H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Binding affinity was evaluated by calculating competition for [3H]spiperone binding on Dopamine receptor D3 expressed on CHO K-1 cells.				J Med Chem 39: 4233-7 (1996) Article DOI: 10.1021/jm960345l BindingDB Entry DOI: 10.7270/Q21C1XJF
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50054076 (7-Dimethylamino-5,6,7,8-tetrahydro-naphthalen-2-ol...) Show SMILES CN(C)C1CCc2ccc(O)cc2C1 Show InChI InChI=1S/C12H17NO/c1-13(2)11-5-3-9-4-6-12(14)8-10(9)7-11/h4,6,8,11,14H,3,5,7H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Binding affinity was evaluated by calculating competition for [3H]N-0437 binding on Dopamine receptor D2L of CHO K-1 cells				J Med Chem 39: 4233-7 (1996) Article DOI: 10.1021/jm960345l BindingDB Entry DOI: 10.7270/Q21C1XJF
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50054076 (7-Dimethylamino-5,6,7,8-tetrahydro-naphthalen-2-ol...) Show SMILES CN(C)C1CCc2ccc(O)cc2C1 Show InChI InChI=1S/C12H17NO/c1-13(2)11-5-3-9-4-6-12(14)8-10(9)7-11/h4,6,8,11,14H,3,5,7H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Binding affinity was evaluated by calculating competition for [3H]spiperone binding on Dopamine receptor D2L of CHO K-1 cells.				J Med Chem 39: 4233-7 (1996) Article DOI: 10.1021/jm960345l BindingDB Entry DOI: 10.7270/Q21C1XJF
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50054076 (7-Dimethylamino-5,6,7,8-tetrahydro-naphthalen-2-ol...) Show SMILES CN(C)C1CCc2ccc(O)cc2C1 Show InChI InChI=1S/C12H17NO/c1-13(2)11-5-3-9-4-6-12(14)8-10(9)7-11/h4,6,8,11,14H,3,5,7H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	729	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Binding affinity was evaluated by calculating competition for [3H]spiperone binding on Dopamine receptor D4.2 of CHO K-1 cells.				J Med Chem 39: 4233-7 (1996) Article DOI: 10.1021/jm960345l BindingDB Entry DOI: 10.7270/Q21C1XJF
					More data for this Ligand-Target Pair