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SMILES: COc1ccccc1-c1ccc(\C=C2/SC(=O)NC2=O)o1

InChI Key: InChIKey=KSBRXTQOZDUEGL-JYRVWZFOSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50054965   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (Human))		BDBM50054965
PNG
(CHEMBL211112)
Show SMILES COc1ccccc1-c1ccc(\C=C2/SC(=O)NC2=O)o1
Show InChI InChI=1S/C15H11NO4S/c1-19-11-5-3-2-4-10(11)12-7-6-9(20-12)8-13-14(17)16-15(18)21-13/h2-8H,1H3,(H,16,17,18)/b13-8-
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Article
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



The University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of PI3Kgamma (unknown origin) assessed as decrease in fluorescence intensity using phosphorylated substrate

Eur J Med Chem 84: 454-65 (2014)


Article DOI: 10.1016/j.ejmech.2014.07.056
BindingDB Entry DOI: 10.7270/Q2057HM8
More data for this
Ligand-Target Pair