null

SMILES: Fc1ccc(NC(=O)CNC(=O)COc2ccc(Cl)cc2)c(F)c1F

InChI Key: InChIKey=VQJHZGKSDAXSNI-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50055464   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine racemase (Homo sapiens (Human))	BDBM50055464 (CHEMBL3317747) Show SMILES Fc1ccc(NC(=O)CNC(=O)COc2ccc(Cl)cc2)c(F)c1F Show InChI InChI=1S/C16H12ClF3N2O3/c17-9-1-3-10(4-2-9)25-8-14(24)21-7-13(23)22-12-6-5-11(18)15(19)16(12)20/h1-6H,7-8H2,(H,21,24)(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.21E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Toyama Curated by ChEMBL					Assay Description Inhibition of full length human recombinant serine recemase C2DC6D mutant expressed in Escherichia coli BL21 (DE3) assessed as D-serine production af...				Bioorg Med Chem Lett 24: 3732-5 (2014) Article DOI: 10.1016/j.bmcl.2014.07.003 BindingDB Entry DOI: 10.7270/Q2PR7XNR
					More data for this Ligand-Target Pair
Serine racemase (Homo sapiens (Human))	BDBM50055464 (CHEMBL3317747) Show SMILES Fc1ccc(NC(=O)CNC(=O)COc2ccc(Cl)cc2)c(F)c1F Show InChI InChI=1S/C16H12ClF3N2O3/c17-9-1-3-10(4-2-9)25-8-14(24)21-7-13(23)22-12-6-5-11(18)15(19)16(12)20/h1-6H,7-8H2,(H,21,24)(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	1.40E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of serine racemase mutant (unknown origin)				Citation and Details Article DOI: 10.1016/j.bmcl.2017.12.021 BindingDB Entry DOI: 10.7270/Q2CV4MB3
					More data for this Ligand-Target Pair
Serine racemase (Homo sapiens (Human))	BDBM50055464 (CHEMBL3317747) Show SMILES Fc1ccc(NC(=O)CNC(=O)COc2ccc(Cl)cc2)c(F)c1F Show InChI InChI=1S/C16H12ClF3N2O3/c17-9-1-3-10(4-2-9)25-8-14(24)21-7-13(23)22-12-6-5-11(18)15(19)16(12)20/h1-6H,7-8H2,(H,21,24)(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	1.60E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of wild-type serine racemase (unknown origin) assessed as residual activity by measuring D-serine level using Dsd1 as substrate and PLP as...				Citation and Details Article DOI: 10.1016/j.bmcl.2017.12.021 BindingDB Entry DOI: 10.7270/Q2CV4MB3
					More data for this Ligand-Target Pair