null
SMILES: Oc1ccccc1C(=O)NNC(=O)c1ccccc1O
InChI Key: InChIKey=UORSDGBOJHYJLV-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Albumin (Bos taurus) | BDBM50056891 (2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | >9.39E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2RX99Q9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50056891 (2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydr...) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Cancer Institute-Frederick Curated by ChEMBL | Assay Description Inhibition of recombinant HIV1 integrase-mediated 3'-processing activity in presence of manganese | J Med Chem 51: 251-9 (2008) Article DOI: 10.1021/jm070715d BindingDB Entry DOI: 10.7270/Q22Z189M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50056891 (2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydr...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.07E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Cancer Institute Curated by ChEMBL | Assay Description Inhibition of HIV-1 integrase enzyme by 3'-processing method | J Med Chem 40: 937-41 (1997) Article DOI: 10.1021/jm960755+ BindingDB Entry DOI: 10.7270/Q2154G4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50056891 (2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydr...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 730 | n/a | n/a | n/a | n/a | n/a | n/a |
National Cancer Institute Curated by ChEMBL | Assay Description Inhibition of HIV-1 integrase enzyme | J Med Chem 40: 937-41 (1997) Article DOI: 10.1021/jm960755+ BindingDB Entry DOI: 10.7270/Q2154G4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50056891 (2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydr...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 730 | n/a | n/a | n/a | n/a | n/a | n/a |
National Cancer Institute Curated by ChEMBL | Assay Description Inhibitory concentration as 50% inhibition of HIV-1 integrase enzyme at strand transfer stage of DNA integration. | J Med Chem 41: 3202-9 (1998) Article DOI: 10.1021/jm9801760 BindingDB Entry DOI: 10.7270/Q28G8JVS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50056891 (2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydr...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.07E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Cancer Institute Curated by ChEMBL | Assay Description Inhibition of HIV-1 integrase enzyme at 3`- processing stage of DNA integration | J Med Chem 41: 3202-9 (1998) Article DOI: 10.1021/jm9801760 BindingDB Entry DOI: 10.7270/Q28G8JVS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50056891 (2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydr...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California Curated by ChEMBL | Assay Description Inhibitory activity against HIV-1 integrase (preincubated with Mg+2, and drug for 30 min followed by DNA for 1h) in strand transfer of preassemble | J Med Chem 45: 5661-70 (2002) BindingDB Entry DOI: 10.7270/Q2M61JMB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50056891 (2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydr...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California Curated by ChEMBL | Assay Description Inhibitory activity against HIV-1 integrase (preincubated with Mg+2, and DNA on ice for 15 min followed by drug for 1h) in 3'' processing of postasse... | J Med Chem 45: 5661-70 (2002) BindingDB Entry DOI: 10.7270/Q2M61JMB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50056891 (2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydr...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California Curated by ChEMBL | Assay Description Inhibitory activity against HIV-1 integrase (preincubated with Mn+2, and DNA on ice for 15 min followed by drug for 1h) in strand transfer of postass... | J Med Chem 45: 5661-70 (2002) BindingDB Entry DOI: 10.7270/Q2M61JMB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50056891 (2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydr...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California Curated by ChEMBL | Assay Description Inhibitory activity against HIV-1 integrase (preincubated with Mg+2, and drug for 30 min followed by DNA for 1h) in 3''-processing of preassemble | J Med Chem 45: 5661-70 (2002) BindingDB Entry DOI: 10.7270/Q2M61JMB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50056891 (2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydr...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California Curated by ChEMBL | Assay Description Inhibitory activity against HIV-1 integrase (preincubated with Mn+2, and drug for 30 min followed by DNA for 1h) in strand transfer of preassemble | J Med Chem 45: 5661-70 (2002) BindingDB Entry DOI: 10.7270/Q2M61JMB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50056891 (2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydr...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California Curated by ChEMBL | Assay Description Inhibitory activity against HIV-1 integrase (preincubated with Mn+2, and DNA on ice for 15 min followed by drug for 1h) in 3'' processing of postasse... | J Med Chem 45: 5661-70 (2002) BindingDB Entry DOI: 10.7270/Q2M61JMB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50056891 (2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydr...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California Curated by ChEMBL | Assay Description Inhibitory activity against HIV-1 integrase (preincubated with Mg+2, and DNA on ice for 15 min followed by drug for 1h) in strand transfer of postass... | J Med Chem 45: 5661-70 (2002) BindingDB Entry DOI: 10.7270/Q2M61JMB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50056891 (2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydr...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California Curated by ChEMBL | Assay Description Inhibitory activity against HIV-1 integrase (preincubated with Mn+2, and drug for 30 min followed by DNA for 1h) in 3''-processing of preassemble | J Med Chem 45: 5661-70 (2002) BindingDB Entry DOI: 10.7270/Q2M61JMB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50056891 (2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydr...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Houston Curated by ChEMBL | Assay Description Inhibitory activity against HIV-1 integrase | Bioorg Med Chem Lett 14: 1447-54 (2004) Article DOI: 10.1016/j.bmcl.2004.01.027 BindingDB Entry DOI: 10.7270/Q2B858PN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50056891 (2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydr...) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >3.33E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
National Cancer Institute-Frederick Curated by ChEMBL | Assay Description Inhibition of recombinant HIV1 integrase-mediated 3'-processing activity in presence of magnesium | J Med Chem 51: 251-9 (2008) Article DOI: 10.1021/jm070715d BindingDB Entry DOI: 10.7270/Q22Z189M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50056891 (2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydr...) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Cancer Institute-Frederick Curated by ChEMBL | Assay Description Inhibition of recombinant HIV1 integrase strand transfer activity in presence of manganese | J Med Chem 51: 251-9 (2008) Article DOI: 10.1021/jm070715d BindingDB Entry DOI: 10.7270/Q22Z189M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50056891 (2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydr...) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >3.33E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
National Cancer Institute-Frederick Curated by ChEMBL | Assay Description Inhibition of recombinant HIV1 integrase strand transfer activity in presence of magnesium | J Med Chem 51: 251-9 (2008) Article DOI: 10.1021/jm070715d BindingDB Entry DOI: 10.7270/Q22Z189M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
T cell receptor alpha variable 4 (Homo sapiens (Human)) | BDBM50056891 (2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydr...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | >9.39E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2WQ02FK | ||||||||||||
More data for this Ligand-Target Pair |