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BDBM50058249 CHEMBL53800::Phenyl-[(3-phenyl-isoquinoline-1-carbonyl)-amino]-acetic acid methyl ester

SMILES: COC(=O)C(NC(=O)c1nc(cc2ccccc12)-c1ccccc1)c1ccccc1

InChI Key: InChIKey=KYTOTOFXLWUDOF-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50058249   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuromedin-K receptor


(Homo sapiens (Human))		BDBM50058249
PNG
(CHEMBL53800 | Phenyl-[(3-phenyl-isoquinoline-1-car...)
Show SMILES COC(=O)C(NC(=O)c1nc(cc2ccccc12)-c1ccccc1)c1ccccc1
Show InChI InChI=1S/C25H20N2O3/c1-30-25(29)22(18-12-6-3-7-13-18)27-24(28)23-20-15-9-8-14-19(20)16-21(26-23)17-10-4-2-5-11-17/h2-16,22H,1H3,(H,27,28)
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



SmithKline Beecham S.p.A. Milano

Curated by ChEMBL


Assay Description
Inhibition of [125I]-MePhe7-Neurokinin B (NKB) binding in human Tachykinin receptor 3 of chinese hamster ovary (hNK-3-CHO) cell membranes.

J Med Chem 40: 1794-807 (1997)


Article DOI: 10.1021/jm960818o
BindingDB Entry DOI: 10.7270/Q24T6HHB
More data for this
Ligand-Target Pair