BDBM50058650 CHEMBL58314::N-[1-(1-benzothien-2-yl)ethyl]-N'-benzyl-N-hydroxyurea

SMILES: CC(N(O)C(=O)NCc1ccccc1)c1cc2ccccc2s1

InChI Key: InChIKey=OPKMOMLBGMFHNK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50058650   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50058650 (CHEMBL58314 | N-[1-(1-benzothien-2-yl)ethyl]-N'-be...) Show SMILES CC(N(O)C(=O)NCc1ccccc1)c1cc2ccccc2s1 Show InChI InChI=1S/C18H18N2O2S/c1-13(17-11-15-9-5-6-10-16(15)23-17)20(22)18(21)19-12-14-7-3-2-4-8-14/h2-11,13,22H,12H2,1H3,(H,19,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase on rat basophil leukemia cell line lysate (RBL-1 2H3 subline) by measuring 5-HETE production				J Med Chem 40: 1955-68 (1997) Article DOI: 10.1021/jm9700474 BindingDB Entry DOI: 10.7270/Q2NV9JWT
					More data for this Ligand-Target Pair