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SMILES: CCNC(=O)c1cc2c(Nc3ccncc3)ncnn2c1

InChI Key: InChIKey=MKUDTVYCMJXTKR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50058683   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase kinase kinase kinase 4


(Homo sapiens (Human))		BDBM50058683
PNG
(CHEMBL3326746)
Show SMILES CCNC(=O)c1cc2c(Nc3ccncc3)ncnn2c1
Show InChI InChI=1S/C14H14N6O/c1-2-16-14(21)10-7-12-13(17-9-18-20(12)8-10)19-11-3-5-15-6-4-11/h3-9H,2H2,1H3,(H,16,21)(H,15,17,18,19)
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n/an/a 640n/an/an/an/an/an/a



Genentech

Curated by ChEMBL


Assay Description
Inhibition of human MAP4K4 using LGRDKYKTLRQIRQ-COOH peptide substrate by LC3K assay

Bioorg Med Chem Lett 24: 4546-52 (2014)


Article DOI: 10.1016/j.bmcl.2014.07.071
BindingDB Entry DOI: 10.7270/Q2NG4S9D
More data for this
Ligand-Target Pair