BDBM50060465 (+) 7-[3-(4-Phenylethynyl-benzenesulfonylamino)-bicyclo[2.2.1]hept-2-yl]-hept-5-enoic acid::(Z)-7-[(1S,2R,3R,4R)-3-(4-Phenylethynyl-benzenesulfonylamino)-bicyclo[2.2.1]hept-2-yl]-hept-5-enoic acid::CHEMBL82489

SMILES: OC(=O)CCC\C=C/C[C@@H]1[C@H]2CC[C@H](C2)[C@H]1NS(=O)(=O)c1ccc(cc1)C#Cc1ccccc1

InChI Key: InChIKey=SDLQZKJKHCYBOV-CWORAHIDSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50060465   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostanoid DP receptor (Homo sapiens (Human))	BDBM50060465 ((+) 7-[3-(4-Phenylethynyl-benzenesulfonylamino)-bi...) Show SMILES OC(=O)CCC\C=C/C[C@@H]1[C@H]2CC[C@H](C2)[C@H]1NS(=O)(=O)c1ccc(cc1)C#Cc1ccccc1 Show InChI InChI=1S/C28H31NO4S/c30-27(31)11-7-2-1-6-10-26-23-16-17-24(20-23)28(26)29-34(32,33)25-18-14-22(15-19-25)13-12-21-8-4-3-5-9-21/h1,3-6,8-9,14-15,18-19,23-24,26,28-29H,2,7,10-11,16-17,20H2,(H,30,31)/b6-1-/t23-,24+,26+,28+/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.60	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of [3H]-PGD-2 specific binding to Prostaglandin D2 receptor fromhuman platelet membranes				J Med Chem 40: 3504-7 (1997) Article DOI: 10.1021/jm970343g BindingDB Entry DOI: 10.7270/Q2959GP9
					More data for this Ligand-Target Pair
Prostanoid IP receptor (Homo sapiens (Human))	BDBM50060465 ((+) 7-[3-(4-Phenylethynyl-benzenesulfonylamino)-bi...) Show SMILES OC(=O)CCC\C=C/C[C@@H]1[C@H]2CC[C@H](C2)[C@H]1NS(=O)(=O)c1ccc(cc1)C#Cc1ccccc1 Show InChI InChI=1S/C28H31NO4S/c30-27(31)11-7-2-1-6-10-26-23-16-17-24(20-23)28(26)29-34(32,33)25-18-14-22(15-19-25)13-12-21-8-4-3-5-9-21/h1,3-6,8-9,14-15,18-19,23-24,26,28-29H,2,7,10-11,16-17,20H2,(H,30,31)/b6-1-/t23-,24+,26+,28+/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of cAMP formation by carbacyclin in Prostaglandin I2 receptor (IP) assay				J Med Chem 40: 3504-7 (1997) Article DOI: 10.1021/jm970343g BindingDB Entry DOI: 10.7270/Q2959GP9
					More data for this Ligand-Target Pair
Prostanoid DP receptor (Homo sapiens (Human))	BDBM50060465 ((+) 7-[3-(4-Phenylethynyl-benzenesulfonylamino)-bi...) Show SMILES OC(=O)CCC\C=C/C[C@@H]1[C@H]2CC[C@H](C2)[C@H]1NS(=O)(=O)c1ccc(cc1)C#Cc1ccccc1 Show InChI InChI=1S/C28H31NO4S/c30-27(31)11-7-2-1-6-10-26-23-16-17-24(20-23)28(26)29-34(32,33)25-18-14-22(15-19-25)13-12-21-8-4-3-5-9-21/h1,3-6,8-9,14-15,18-19,23-24,26,28-29H,2,7,10-11,16-17,20H2,(H,30,31)/b6-1-/t23-,24+,26+,28+/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.5	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibition of [3H]- PGD-2 radioligand binding to prostaglandin D2 receptor on human platelet membrane				J Med Chem 46: 2436-45 (2003) Article DOI: 10.1021/jm020517g BindingDB Entry DOI: 10.7270/Q2154GFS
					More data for this Ligand-Target Pair
Prostanoid DP receptor (Homo sapiens (Human))	BDBM50060465 ((+) 7-[3-(4-Phenylethynyl-benzenesulfonylamino)-bi...) Show SMILES OC(=O)CCC\C=C/C[C@@H]1[C@H]2CC[C@H](C2)[C@H]1NS(=O)(=O)c1ccc(cc1)C#Cc1ccccc1 Show InChI InChI=1S/C28H31NO4S/c30-27(31)11-7-2-1-6-10-26-23-16-17-24(20-23)28(26)29-34(32,33)25-18-14-22(15-19-25)13-12-21-8-4-3-5-9-21/h1,3-6,8-9,14-15,18-19,23-24,26,28-29H,2,7,10-11,16-17,20H2,(H,30,31)/b6-1-/t23-,24+,26+,28+/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of cAMP formation evoked by the prostaglandin D2 receptor in human platelets				J Med Chem 40: 3504-7 (1997) Article DOI: 10.1021/jm970343g BindingDB Entry DOI: 10.7270/Q2959GP9
					More data for this Ligand-Target Pair
Prostanoid DP receptor (Homo sapiens (Human))	BDBM50060465 ((+) 7-[3-(4-Phenylethynyl-benzenesulfonylamino)-bi...) Show SMILES OC(=O)CCC\C=C/C[C@@H]1[C@H]2CC[C@H](C2)[C@H]1NS(=O)(=O)c1ccc(cc1)C#Cc1ccccc1 Show InChI InChI=1S/C28H31NO4S/c30-27(31)11-7-2-1-6-10-26-23-16-17-24(20-23)28(26)29-34(32,33)25-18-14-22(15-19-25)13-12-21-8-4-3-5-9-21/h1,3-6,8-9,14-15,18-19,23-24,26,28-29H,2,7,10-11,16-17,20H2,(H,30,31)/b6-1-/t23-,24+,26+,28+/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibition of cAMP formation evoked by prostaglandin D2 receptor in human platelets				J Med Chem 46: 2436-45 (2003) Article DOI: 10.1021/jm020517g BindingDB Entry DOI: 10.7270/Q2154GFS
					More data for this Ligand-Target Pair
Prostanoid TP receptor (Homo sapiens (Human))	BDBM50060465 ((+) 7-[3-(4-Phenylethynyl-benzenesulfonylamino)-bi...) Show SMILES OC(=O)CCC\C=C/C[C@@H]1[C@H]2CC[C@H](C2)[C@H]1NS(=O)(=O)c1ccc(cc1)C#Cc1ccccc1 Show InChI InChI=1S/C28H31NO4S/c30-27(31)11-7-2-1-6-10-26-23-16-17-24(20-23)28(26)29-34(32,33)25-18-14-22(15-19-25)13-12-21-8-4-3-5-9-21/h1,3-6,8-9,14-15,18-19,23-24,26,28-29H,2,7,10-11,16-17,20H2,(H,30,31)/b6-1-/t23-,24+,26+,28+/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of [3H]- (+)-S-145 specific binding to human platelet membranes in TXA2 receptor (TP) assay				J Med Chem 40: 3504-7 (1997) Article DOI: 10.1021/jm970343g BindingDB Entry DOI: 10.7270/Q2959GP9
					More data for this Ligand-Target Pair