BDBM50062138 4-Trifluoromethyl-piperidin-(2Z)-ylideneamine::CHEMBL268312

SMILES: NC1=NCCC(C1)C(F)(F)F

InChI Key: InChIKey=HTZZMLFQUNRRMS-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50062138   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nitric oxide synthase, brain (Homo sapiens (Human))	BDBM50062138 (4-Trifluoromethyl-piperidin-(2Z)-ylideneamine | CH...) Show SMILES NC1=NCCC(C1)C(F)(F)F |t:1| Show InChI InChI=1S/C6H9F3N2/c7-6(8,9)4-1-2-11-5(10)3-4/h4H,1-3H2,(H2,10,11)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle Research and Development Curated by ChEMBL					Assay Description Inhibition of human Neuronal nitric oxide synthase				J Med Chem 41: 96-101 (1998) Article DOI: 10.1021/jm9705059 BindingDB Entry DOI: 10.7270/Q2GM86D2
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Homo sapiens (Human))	BDBM50062138 (4-Trifluoromethyl-piperidin-(2Z)-ylideneamine | CH...) Show SMILES NC1=NCCC(C1)C(F)(F)F |t:1| Show InChI InChI=1S/C6H9F3N2/c7-6(8,9)4-1-2-11-5(10)3-4/h4H,1-3H2,(H2,10,11)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	4.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle Research and Development Curated by ChEMBL					Assay Description inhibition of human endothelial constitutive Endothelial nitric oxide synthase (heNOS)				J Med Chem 41: 96-101 (1998) Article DOI: 10.1021/jm9705059 BindingDB Entry DOI: 10.7270/Q2GM86D2
					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50062138 (4-Trifluoromethyl-piperidin-(2Z)-ylideneamine | CH...) Show SMILES NC1=NCCC(C1)C(F)(F)F |t:1| Show InChI InChI=1S/C6H9F3N2/c7-6(8,9)4-1-2-11-5(10)3-4/h4H,1-3H2,(H2,10,11)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle Research and Development Curated by ChEMBL					Assay Description Inhibition of human Inducible nitric oxide synthase				J Med Chem 41: 96-101 (1998) Article DOI: 10.1021/jm9705059 BindingDB Entry DOI: 10.7270/Q2GM86D2
					More data for this Ligand-Target Pair