BDBM50062139 5-Methyl-piperidin-(2Z)-ylideneamine::CHEMBL269330
SMILES: CC1CCC(N)=NC1
InChI Key: InChIKey=OQYPAQURYOEEGO-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nitric oxide synthase, brain (Homo sapiens (Human)) | BDBM50062139![]() (5-Methyl-piperidin-(2Z)-ylideneamine | CHEMBL26933...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
G. D. Searle Research and Development Curated by ChEMBL | Assay Description Inhibition of human Neuronal nitric oxide synthase | J Med Chem 41: 96-101 (1998) Article DOI: 10.1021/jm9705059 BindingDB Entry DOI: 10.7270/Q2GM86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, endothelial (Homo sapiens (Human)) | BDBM50062139![]() (5-Methyl-piperidin-(2Z)-ylideneamine | CHEMBL26933...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
G. D. Searle Research and Development Curated by ChEMBL | Assay Description inhibition of human endothelial constitutive Endothelial nitric oxide synthase (heNOS) | J Med Chem 41: 96-101 (1998) Article DOI: 10.1021/jm9705059 BindingDB Entry DOI: 10.7270/Q2GM86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, inducible (Homo sapiens (Human)) | BDBM50062139![]() (5-Methyl-piperidin-(2Z)-ylideneamine | CHEMBL26933...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
G. D. Searle Research and Development Curated by ChEMBL | Assay Description Inhibition of human Inducible nitric oxide synthase | J Med Chem 41: 96-101 (1998) Article DOI: 10.1021/jm9705059 BindingDB Entry DOI: 10.7270/Q2GM86D2 | |||||||||||
More data for this Ligand-Target Pair |