BDBM50062394 1N-cyanoimino(tert-pentylamino)methyl-4-iodoaniline::CHEMBL328308
SMILES: CCC(C)(C)NC(Nc1ccc(I)cc1)=NC#N
InChI Key: InChIKey=PSCXSSQRAGJZST-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human)) | BDBM50062394 (1N-cyanoimino(tert-pentylamino)methyl-4-iodoanilin...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 74 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding affinity was determined by displacement of [3H]-P1075 from its binding sites in canine cardiac membranes | J Med Chem 41: 271-5 (1998) Article DOI: 10.1021/jm970762d BindingDB Entry DOI: 10.7270/Q2FN159P | |||||||||||
More data for this Ligand-Target Pair |