BDBM50062510 (S)-2-((R)-1-Amino-1-carboxy-4,4-diphenyl-butyl)-cyclopropanecarboxylic acid::CHEMBL333487
SMILES: N[C@](CCC(c1ccccc1)c1ccccc1)(C1C[C@@H]1C(O)=O)C(O)=O
InChI Key: InChIKey=MYZZJMFAJXSPSC-KXXXGBTESA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor 3 (Homo sapiens (Human)) | BDBM50062510 ((S)-2-((R)-1-Amino-1-carboxy-4,4-diphenyl-butyl)-c...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Ability to block 1S,3R-ACPD-induced inhibition of forskolin stimulated cyclic-AMP in non-neuronal cell line expressing human Metabotropic glutamate r... | J Med Chem 41: 346-57 (1998) Article DOI: 10.1021/jm970497w BindingDB Entry DOI: 10.7270/Q22F7MJ0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50062510 ((S)-2-((R)-1-Amino-1-carboxy-4,4-diphenyl-butyl)-c...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Ability to block 1S,3R-ACPD-induced inhibition of forskolin stimulated cyclic-AMP in non-neuronal cell line expressing human Metabotropic glutamate r... | J Med Chem 41: 346-57 (1998) Article DOI: 10.1021/jm970497w BindingDB Entry DOI: 10.7270/Q22F7MJ0 | |||||||||||
More data for this Ligand-Target Pair |