BDBM50063247 4-(2-Benzhydryloxy-ethyl)-1-[3-(4-fluoro-phenyl)-propyl]-piperidine::CHEMBL350057
SMILES: Fc1ccc(CCCN2CCC(CCOC(c3ccccc3)c3ccccc3)CC2)cc1
InChI Key: InChIKey=URHDHOCAMMJPFU-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50063247![]() (4-(2-Benzhydryloxy-ethyl)-1-[3-(4-fluoro-phenyl)-p...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 223 | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc. Curated by ChEMBL | Assay Description Inhibitory activity against serotonin transporter (SERT) labeled with [3H]-citalopram in rat brain striatal membrane. | J Med Chem 41: 699-705 (1998) Article DOI: 10.1021/jm970595h BindingDB Entry DOI: 10.7270/Q247491Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50063247![]() (4-(2-Benzhydryloxy-ethyl)-1-[3-(4-fluoro-phenyl)-p...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc. Curated by ChEMBL | Assay Description Inhibitory activity against dopamine transporter (DAT) labeled with [3H]-WIN- 35,428 in rat brain striatal membrane. | J Med Chem 41: 699-705 (1998) Article DOI: 10.1021/jm970595h BindingDB Entry DOI: 10.7270/Q247491Z | |||||||||||
More data for this Ligand-Target Pair |