BDBM50063268 1,1-Dimethyl-4-(7,8,9,10-tetrahydro-phenanthridin-6-yl)-piperazin-1-ium::CHEMBL163595
SMILES: C[N+]1(C)CCN(CC1)c1nc2ccccc2c2CCCCc12
InChI Key: InChIKey=YYRWMHFDEFDRNC-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT) | BDBM50063268 (1,1-Dimethyl-4-(7,8,9,10-tetrahydro-phenanthridin-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Siena Curated by ChEMBL | Assay Description Ability to displace [3H]granisetron specifically bound to 5-hydroxytryptamine 3 receptor in rat cortical membrane | J Med Chem 41: 728-41 (1998) Article DOI: 10.1021/jm970645i BindingDB Entry DOI: 10.7270/Q2QV3N6F | |||||||||||
More data for this Ligand-Target Pair |