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SMILES: COc1cccc(NC(=O)NNc2nc3ccccc3c(=O)n2-c2cccc(OC(C)C)c2)c1

InChI Key: InChIKey=QWUOJZKXQRFGRI-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50063648   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gastrin/cholecystokinin type B receptor


(MOUSE)		BDBM50063648
PNG
(CHEMBL8922 | N-(3-methoxyphenyl)-2-[3,4-dihydro-3-...)
Show SMILES COc1cccc(NC(=O)NNc2nc3ccccc3c(=O)n2-c2cccc(OC(C)C)c2)c1
Show InChI InChI=1S/C25H25N5O4/c1-16(2)34-20-11-7-9-18(15-20)30-23(31)21-12-4-5-13-22(21)27-24(30)28-29-25(32)26-17-8-6-10-19(14-17)33-3/h4-16H,1-3H3,(H,27,28)(H2,26,29,32)
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Article
PubMed
n/an/a 22n/an/an/an/an/an/a



Parke-Davis Pharmaceutical Research

Curated by ChEMBL


Assay Description
Binding affinity towards Cholecystokinin type B receptor (CCK-B) receptor in mouse cerebral cortex using [125I]-Bolton Hunter CCK-8 as radioligand

J Med Chem 41: 1042-9 (1998)


Article DOI: 10.1021/jm970373j
BindingDB Entry DOI: 10.7270/Q2TQ60N3
More data for this
Ligand-Target Pair
Cholecystokinin receptor type A


(RAT)		BDBM50063648
PNG
(CHEMBL8922 | N-(3-methoxyphenyl)-2-[3,4-dihydro-3-...)
Show SMILES COc1cccc(NC(=O)NNc2nc3ccccc3c(=O)n2-c2cccc(OC(C)C)c2)c1
Show InChI InChI=1S/C25H25N5O4/c1-16(2)34-20-11-7-9-18(15-20)30-23(31)21-12-4-5-13-22(21)27-24(30)28-29-25(32)26-17-8-6-10-19(14-17)33-3/h4-16H,1-3H3,(H,27,28)(H2,26,29,32)
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PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 7.47E+3n/an/an/an/an/an/a



Parke-Davis Pharmaceutical Research

Curated by ChEMBL


Assay Description
Binding affinity towards Cholecystokinin type A receptor (CCK-A) receptor from rat pancreas using [125I]-Bolton Hunter CCK-8 as radioligand

J Med Chem 41: 1042-9 (1998)


Article DOI: 10.1021/jm970373j
BindingDB Entry DOI: 10.7270/Q2TQ60N3
More data for this
Ligand-Target Pair