BDBM50064183 (2E,4E)-5-(5,6-Dichloro-1H-indol-2-yl)-2-methoxy-penta-2,4-dienoic acid methyl ester::CHEMBL39097

SMILES: COC(=O)C(\OC)=C/C=C/c1cc2cc(Cl)c(Cl)cc2[nH]1

InChI Key: InChIKey=VUONTIGZNJVBHV-ORRXZRLISA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50064183   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vacuolar ATP synthase subunit S1 (Homo sapiens (Human))	BDBM50064183 ((2E,4E)-5-(5,6-Dichloro-1H-indol-2-yl)-2-methoxy-p...) Show SMILES COC(=O)C(\OC)=C/C=C/c1cc2cc(Cl)c(Cl)cc2[nH]1 Show InChI InChI=1S/C15H13Cl2NO3/c1-20-14(15(19)21-2)5-3-4-10-6-9-7-11(16)12(17)8-13(9)18-10/h3-8,18H,1-2H3/b4-3+,14-5+	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Compound was tested for inhibititon of V-ATPase from Chicken osteoclasts (cOc)				J Med Chem 41: 1568-73 (1998) Article DOI: 10.1021/jm9800144 BindingDB Entry DOI: 10.7270/Q2CJ8CM6
					More data for this Ligand-Target Pair