BindingDB PrimarySearch

BDBM50064342 (R)-2-[(S)-1-((S)-5-Acetylamino-1-methylcarbamoyl-pentylcarbamoyl)-3-phenyl-propylamino]-4-methylcarbamoyl-butyric acid::CHEMBL48786

SMILES: CNC(=O)CC[C@@H](N[C@@H](CCc1ccccc1)C(=O)N[C@@H](CCCCNC(C)=O)C(=O)NC)C(O)=O

InChI Key: InChIKey=WMVFFTPYCGKWCT-PCCBWWKXSA-N

Data: 5 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50064342
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Neutrophil collagenase (Homo sapiens (Human))	BDBM50064342 ((R)-2-[(S)-1-((S)-5-Acetylamino-1-methylcarbamoyl-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	293	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The DuPont Merck Pharmaceutical Co. Curated by ChEMBL					Assay Description Inhibition of Matrix metalloproteinase-8				J Med Chem 41: 1749-51 (1998) Article DOI: 10.1021/jm970850y BindingDB Entry DOI: 10.7270/Q2BK1BFX
The DuPont Merck Pharmaceutical Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50064342 ((R)-2-[(S)-1-((S)-5-Acetylamino-1-methylcarbamoyl-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	404	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The DuPont Merck Pharmaceutical Co. Curated by ChEMBL					Assay Description Inhibition of Matrix metalloproteinase-9				J Med Chem 41: 1749-51 (1998) Article DOI: 10.1021/jm970850y BindingDB Entry DOI: 10.7270/Q2BK1BFX
The DuPont Merck Pharmaceutical Co. Curated by ChEMBL					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50064342 ((R)-2-[(S)-1-((S)-5-Acetylamino-1-methylcarbamoyl-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	1.53E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The DuPont Merck Pharmaceutical Co. Curated by ChEMBL					Assay Description Inhibition of Matrix metalloproteinase-2				J Med Chem 41: 1749-51 (1998) Article DOI: 10.1021/jm970850y BindingDB Entry DOI: 10.7270/Q2BK1BFX
The DuPont Merck Pharmaceutical Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50064342 ((R)-2-[(S)-1-((S)-5-Acetylamino-1-methylcarbamoyl-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	2.86E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The DuPont Merck Pharmaceutical Co. Curated by ChEMBL					Assay Description Inhibition of Matrix metalloproteinase-1				J Med Chem 41: 1749-51 (1998) Article DOI: 10.1021/jm970850y BindingDB Entry DOI: 10.7270/Q2BK1BFX
The DuPont Merck Pharmaceutical Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50064342 ((R)-2-[(S)-1-((S)-5-Acetylamino-1-methylcarbamoyl-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	1.41E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The DuPont Merck Pharmaceutical Co. Curated by ChEMBL					Assay Description Inhibition of Matrix metalloproteinase-3				J Med Chem 41: 1749-51 (1998) Article DOI: 10.1021/jm970850y BindingDB Entry DOI: 10.7270/Q2BK1BFX
The DuPont Merck Pharmaceutical Co. Curated by ChEMBL					More data for this Ligand-Target Pair