BDBM50067284 (E)-N-({[2,4-Dichloro-3-(3-methyl-quinoxalin-5-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-3-[4-(2-oxo-pyrrolidin-1-yl)-phenyl]-acrylamide::CHEMBL130782

SMILES: CN(C(=O)CNC(=O)\C=C\c1ccc(cc1)N1CCCC1=O)c1ccc(Cl)c(COc2cccc3ncc(C)nc23)c1Cl

InChI Key: InChIKey=ZPHVGSMDDQJJLW-XNTDXEJSSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50067284   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
BDKRB2 (Homo sapiens (Human))	BDBM50067284 ((E)-N-({[2,4-Dichloro-3-(3-methyl-quinoxalin-5-ylo...) Show SMILES CN(C(=O)CNC(=O)\C=C\c1ccc(cc1)N1CCCC1=O)c1ccc(Cl)c(COc2cccc3ncc(C)nc23)c1Cl Show InChI InChI=1S/C32H29Cl2N5O4/c1-20-17-35-25-5-3-6-27(32(25)37-20)43-19-23-24(33)13-14-26(31(23)34)38(2)30(42)18-36-28(40)15-10-21-8-11-22(12-9-21)39-16-4-7-29(39)41/h3,5-6,8-15,17H,4,7,16,18-19H2,1-2H3,(H,36,40)/b15-10+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Fujisawa Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition specific binding of [3H]BK (1.0 nM) to human Bradykinin receptor B2 which was expressed in CHO (Chinese hamster ovary) cells by 50%.				J Med Chem 41: 4062-79 (1998) Article DOI: 10.1021/jm980300f BindingDB Entry DOI: 10.7270/Q2RX9CS1
					More data for this Ligand-Target Pair
Bradykinin B2 receptor (Cavia porcellus)	BDBM50067284 ((E)-N-({[2,4-Dichloro-3-(3-methyl-quinoxalin-5-ylo...) Show SMILES CN(C(=O)CNC(=O)\C=C\c1ccc(cc1)N1CCCC1=O)c1ccc(Cl)c(COc2cccc3ncc(C)nc23)c1Cl Show InChI InChI=1S/C32H29Cl2N5O4/c1-20-17-35-25-5-3-6-27(32(25)37-20)43-19-23-24(33)13-14-26(31(23)34)38(2)30(42)18-36-28(40)15-10-21-8-11-22(12-9-21)39-16-4-7-29(39)41/h3,5-6,8-15,17H,4,7,16,18-19H2,1-2H3,(H,36,40)/b15-10+	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Fujisawa Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Concentration required to inhibit specific binding of [ 3H]BK (0.06 nM) to Bradykinin receptor B2 in guinea pig ileum membrane preparations by 50%.				J Med Chem 41: 4062-79 (1998) Article DOI: 10.1021/jm980300f BindingDB Entry DOI: 10.7270/Q2RX9CS1
					More data for this Ligand-Target Pair