BDBM50067343 CHEMBL1574987

SMILES: CCOc1ccc(cc1)-c1csc2ncnc(Nc3cccc(O)c3)c12

InChI Key: InChIKey=BRIAXUXTUXJMKY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50067343   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50067343 (CHEMBL1574987) Show SMILES CCOc1ccc(cc1)-c1csc2ncnc(Nc3cccc(O)c3)c12 Show InChI InChI=1S/C20H17N3O2S/c1-2-25-16-8-6-13(7-9-16)17-11-26-20-18(17)19(21-12-22-20)23-14-4-3-5-15(24)10-14/h3-12,24H,2H2,1H3,(H,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Molecular Biology and Genetics NAS of Ukraine Curated by ChEMBL					Assay Description Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...				Bioorg Med Chem 23: 2287-93 (2015) Article DOI: 10.1016/j.bmc.2014.12.044 BindingDB Entry DOI: 10.7270/Q2RB7692
					More data for this Ligand-Target Pair