BDBM50067475 CHEMBL3400166

SMILES: CC(C)[C@H](N1C(=S)S\C(=C/c2ccc(cc2)-c2ccccc2)C1=O)C(=O)NS(=O)(=O)c1ccccc1

InChI Key: InChIKey=LCGFXQFEZVBSNX-PSJJOBAMSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50067475   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM50067475 (CHEMBL3400166) Show SMILES CC(C)[C@H](N1C(=S)S\C(=C/c2ccc(cc2)-c2ccccc2)C1=O)C(=O)NS(=O)(=O)c1ccccc1 |r| Show InChI InChI=1S/C27H24N2O4S3/c1-18(2)24(25(30)28-36(32,33)22-11-7-4-8-12-22)29-26(31)23(35-27(29)34)17-19-13-15-21(16-14-19)20-9-5-3-6-10-20/h3-18,24H,1-2H3,(H,28,30)/b23-17-/t24-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	630	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of Bcl-XL (unknown origin) using 5-FAM-Bid-BH3 as substrate preincubated for 30 mins before substrate addition measured after 20 mins by f...				Bioorg Med Chem 23: 1994-2003 (2015) Article DOI: 10.1016/j.bmc.2015.03.024 BindingDB Entry DOI: 10.7270/Q2C24Z35
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