BDBM50067528 3-(3-Carbamimidoyl-phenyl)-2-[2-(4-thiocarbamoyl-benzenesulfonylamino)-acetylamino]-propionic acid ethyl ester::CHEMBL336844
SMILES: CCOC(=O)C(Cc1cccc(c1)C(N)=N)NC(=O)CNS(=O)(=O)c1ccc(cc1)C(N)=S
InChI Key: InChIKey=YFHANJZAFYUYQQ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Coagulation factor X (Bos taurus) | BDBM50067528 (3-(3-Carbamimidoyl-phenyl)-2-[2-(4-thiocarbamoyl-b...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 580 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut für Biochemie Curated by ChEMBL | Assay Description Inhibitory activity against Coagulation factor X | J Med Chem 41: 4240-50 (1998) Article DOI: 10.1021/jm980227t BindingDB Entry DOI: 10.7270/Q27D2T86 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50067528 (3-(3-Carbamimidoyl-phenyl)-2-[2-(4-thiocarbamoyl-b...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 640 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut für Biochemie Curated by ChEMBL | Assay Description Inhibitory activity against Coagulation factor X | J Med Chem 41: 4240-50 (1998) Article DOI: 10.1021/jm980227t BindingDB Entry DOI: 10.7270/Q27D2T86 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasma kallikrein (Homo sapiens (Human)) | BDBM50067528 (3-(3-Carbamimidoyl-phenyl)-2-[2-(4-thiocarbamoyl-b...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut für Biochemie Curated by ChEMBL | Assay Description Inhibitory activity against plasma kallikrein | J Med Chem 41: 4240-50 (1998) Article DOI: 10.1021/jm980227t BindingDB Entry DOI: 10.7270/Q27D2T86 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypsin II (Bos taurus) | BDBM50067528 (3-(3-Carbamimidoyl-phenyl)-2-[2-(4-thiocarbamoyl-b...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut für Biochemie Curated by ChEMBL | Assay Description Inhibitory activity against Trypsin. | J Med Chem 41: 4240-50 (1998) Article DOI: 10.1021/jm980227t BindingDB Entry DOI: 10.7270/Q27D2T86 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thrombin (Bos taurus (Bovine)) | BDBM50067528 (3-(3-Carbamimidoyl-phenyl)-2-[2-(4-thiocarbamoyl-b...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut für Biochemie Curated by ChEMBL | Assay Description Inhibitory activity against Thrombin. | J Med Chem 41: 4240-50 (1998) Article DOI: 10.1021/jm980227t BindingDB Entry DOI: 10.7270/Q27D2T86 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin K-dependent protein C (Homo sapiens (Human)) | BDBM50067528 (3-(3-Carbamimidoyl-phenyl)-2-[2-(4-thiocarbamoyl-b...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut für Biochemie Curated by ChEMBL | Assay Description Inhibitory activity against the anticoagulant Activated protein C | J Med Chem 41: 4240-50 (1998) Article DOI: 10.1021/jm980227t BindingDB Entry DOI: 10.7270/Q27D2T86 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasminogen (Homo sapiens (Human)) | BDBM50067528 (3-(3-Carbamimidoyl-phenyl)-2-[2-(4-thiocarbamoyl-b...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut für Biochemie Curated by ChEMBL | Assay Description Inhibitory activity against Plasmin. | J Med Chem 41: 4240-50 (1998) Article DOI: 10.1021/jm980227t BindingDB Entry DOI: 10.7270/Q27D2T86 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urokinase-type plasminogen activator (Homo sapiens (Human)) | BDBM50067528 (3-(3-Carbamimidoyl-phenyl)-2-[2-(4-thiocarbamoyl-b...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut für Biochemie Curated by ChEMBL | Assay Description Inhibitory activity against microPa. | J Med Chem 41: 4240-50 (1998) Article DOI: 10.1021/jm980227t BindingDB Entry DOI: 10.7270/Q27D2T86 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptase (Homo sapiens (Human)) | BDBM50067528 (3-(3-Carbamimidoyl-phenyl)-2-[2-(4-thiocarbamoyl-b...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut für Biochemie Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against Tryptase. | J Med Chem 41: 4240-50 (1998) Article DOI: 10.1021/jm980227t BindingDB Entry DOI: 10.7270/Q27D2T86 | |||||||||||
More data for this Ligand-Target Pair |