BDBM50068847 (S)-N-Hydroxy-2-[(4-methoxy-benzenesulfonyl)-pyridin-2-ylmethyl-amino]-3-methyl-butyramide::CHEMBL353941

SMILES: COc1ccc(cc1)S(=O)(=O)N(Cc1ccccn1)[C@@H](C(C)C)C(=O)NO

InChI Key: InChIKey=ALGODWWXKQXHJA-KRWDZBQOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50068847   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase 12 (Mus musculus)	BDBM50068847 ((S)-N-Hydroxy-2-[(4-methoxy-benzenesulfonyl)-pyrid...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccn1)[C@@H](C(C)C)C(=O)NO Show InChI InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-6-4-5-11-19-14)27(24,25)16-9-7-15(26-3)8-10-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against mouse macrophage metalloelastase (MME) using [3H]elastin as a substrate				Bioorg Med Chem Lett 8: 897-902 (1999) BindingDB Entry DOI: 10.7270/Q2NP24ZC
					More data for this Ligand-Target Pair