BDBM50068849 (R)-2-[(4-Methoxy-benzenesulfonyl)-pyridin-2-ylmethyl-amino]-4-methyl-pentanoic acid hydroxyamide::CHEMBL170040

SMILES: COc1ccc(cc1)S(=O)(=O)N(Cc1ccccn1)[C@H](CC(C)C)C(=O)NO

InChI Key: InChIKey=UYFFUIVYRNCEPG-GOSISDBHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50068849   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase 12 (Mus musculus)	BDBM50068849 ((R)-2-[(4-Methoxy-benzenesulfonyl)-pyridin-2-ylmet...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccn1)[C@H](CC(C)C)C(=O)NO Show InChI InChI=1S/C19H25N3O5S/c1-14(2)12-18(19(23)21-24)22(13-15-6-4-5-11-20-15)28(25,26)17-9-7-16(27-3)8-10-17/h4-11,14,18,24H,12-13H2,1-3H3,(H,21,23)/t18-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	6.90	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against mouse macrophage metalloelastase (MME) using [3H]elastin as a substrate				Bioorg Med Chem Lett 8: 897-902 (1999) BindingDB Entry DOI: 10.7270/Q2NP24ZC
					More data for this Ligand-Target Pair