BDBM50069207 CHEMBL3402444

SMILES: Nc1cccc(CNC(=O)Nc2ccc(cc2)-c2cn[nH]c2)c1

InChI Key: InChIKey=YXNKLABYTKPQJO-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50069207   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50069207 (CHEMBL3402444) Show SMILES Nc1cccc(CNC(=O)Nc2ccc(cc2)-c2cn[nH]c2)c1 Show InChI InChI=1S/C17H17N5O/c18-15-3-1-2-12(8-15)9-19-17(23)22-16-6-4-13(5-7-16)14-10-20-21-11-14/h1-8,10-11H,9,18H2,(H,20,21)(H2,19,22,23)	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Technology Curated by ChEMBL					Assay Description Inhibition of ROCK2 (unknown origin) using STK2 substrate after 4 hrs by HTRF mode				Bioorg Med Chem 23: 2505-17 (2015) Article DOI: 10.1016/j.bmc.2015.03.047 BindingDB Entry DOI: 10.7270/Q2ZP47SX
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50069207 (CHEMBL3402444) Show SMILES Nc1cccc(CNC(=O)Nc2ccc(cc2)-c2cn[nH]c2)c1 Show InChI InChI=1S/C17H17N5O/c18-15-3-1-2-12(8-15)9-19-17(23)22-16-6-4-13(5-7-16)14-10-20-21-11-14/h1-8,10-11H,9,18H2,(H,20,21)(H2,19,22,23)	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Technology Curated by ChEMBL					Assay Description Inhibition of ROCK2 (unknown origin) using STK2 substrate after 4 hrs by HTRF mode				Bioorg Med Chem 23: 2505-17 (2015) Article DOI: 10.1016/j.bmc.2015.03.047 BindingDB Entry DOI: 10.7270/Q2ZP47SX
					More data for this Ligand-Target Pair