BDBM50070553 CHEMBL3408801
SMILES: Nc1ncnc2c3cc(cnc3sc12)-c1ccc(F)cc1F
InChI Key: InChIKey=GAMSOECPTUHWGO-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dual specificty protein kinase CLK1 (Homo sapiens (Human)) | BDBM50070553 (CHEMBL3408801) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
UMR 6014& FR 3038; Univ Rouen; INSA Rouen; CNRS Curated by ChEMBL | Assay Description Inhibition of human recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate after 30 mins | Eur J Med Chem 92: 124-34 (2015) Article DOI: 10.1016/j.ejmech.2014.12.038 BindingDB Entry DOI: 10.7270/Q2BR8TVG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (RAT) | BDBM50070553 (CHEMBL3408801) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UMR 6014& FR 3038; Univ Rouen; INSA Rouen; CNRS Curated by ChEMBL | Assay Description Inhibition of rat recombinant GST-tagged DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation counti... | Eur J Med Chem 92: 124-34 (2015) Article DOI: 10.1016/j.ejmech.2014.12.038 BindingDB Entry DOI: 10.7270/Q2BR8TVG | |||||||||||
More data for this Ligand-Target Pair |