BDBM50070615 CHEMBL3409039

SMILES: O=C(CCCCN1CCN(CC1)c1ccccc1-c1ccccc1)N1CCC[C@H]1C(=O)N1CCCCC1

InChI Key: InChIKey=CWYCYSJSUHLIBI-LJAQVGFWSA-N

Data: 6 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50070615   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50070615 (CHEMBL3409039) Show SMILES O=C(CCCCN1CCN(CC1)c1ccccc1-c1ccccc1)N1CCC[C@H]1C(=O)N1CCCCC1 |r| Show InChI InChI=1S/C31H42N4O2/c36-30(35-21-11-16-29(35)31(37)34-19-8-2-9-20-34)17-7-10-18-32-22-24-33(25-23-32)28-15-6-5-14-27(28)26-12-3-1-4-13-26/h1,3-6,12-15,29H,2,7-11,16-25H2/t29-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from human 5HT7 receptor expressed in HEK293 cells after 1 hr				Eur J Med Chem 92: 202-11 (2015) Article DOI: 10.1016/j.ejmech.2014.12.041 BindingDB Entry DOI: 10.7270/Q2TT4SNW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50070615 (CHEMBL3409039) Show SMILES O=C(CCCCN1CCN(CC1)c1ccccc1-c1ccccc1)N1CCC[C@H]1C(=O)N1CCCCC1 |r| Show InChI InChI=1S/C31H42N4O2/c36-30(35-21-11-16-29(35)31(37)34-19-8-2-9-20-34)17-7-10-18-32-22-24-33(25-23-32)28-15-6-5-14-27(28)26-12-3-1-4-13-26/h1,3-6,12-15,29H,2,7-11,16-25H2/t29-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Agonist activity at human 5HT7 receptor expressed in HEK293 cells assessed as cAMP concentration at 10'-6 M by adenylate cyclase activity based HTRF ...				Eur J Med Chem 92: 202-11 (2015) Article DOI: 10.1016/j.ejmech.2014.12.041 BindingDB Entry DOI: 10.7270/Q2TT4SNW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50070615 (CHEMBL3409039) Show SMILES O=C(CCCCN1CCN(CC1)c1ccccc1-c1ccccc1)N1CCC[C@H]1C(=O)N1CCCCC1 |r| Show InChI InChI=1S/C31H42N4O2/c36-30(35-21-11-16-29(35)31(37)34-19-8-2-9-20-34)17-7-10-18-32-22-24-33(25-23-32)28-15-6-5-14-27(28)26-12-3-1-4-13-26/h1,3-6,12-15,29H,2,7-11,16-25H2/t29-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells after 1 hr				Eur J Med Chem 92: 202-11 (2015) Article DOI: 10.1016/j.ejmech.2014.12.041 BindingDB Entry DOI: 10.7270/Q2TT4SNW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50070615 (CHEMBL3409039) Show SMILES O=C(CCCCN1CCN(CC1)c1ccccc1-c1ccccc1)N1CCC[C@H]1C(=O)N1CCCCC1 |r| Show InChI InChI=1S/C31H42N4O2/c36-30(35-21-11-16-29(35)31(37)34-19-8-2-9-20-34)17-7-10-18-32-22-24-33(25-23-32)28-15-6-5-14-27(28)26-12-3-1-4-13-26/h1,3-6,12-15,29H,2,7-11,16-25H2/t29-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Antagonist activity at human 5HT7 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP concentration at 10'-6 M by ade...				Eur J Med Chem 92: 202-11 (2015) Article DOI: 10.1016/j.ejmech.2014.12.041 BindingDB Entry DOI: 10.7270/Q2TT4SNW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50070615 (CHEMBL3409039) Show SMILES O=C(CCCCN1CCN(CC1)c1ccccc1-c1ccccc1)N1CCC[C@H]1C(=O)N1CCCCC1 |r| Show InChI InChI=1S/C31H42N4O2/c36-30(35-21-11-16-29(35)31(37)34-19-8-2-9-20-34)17-7-10-18-32-22-24-33(25-23-32)28-15-6-5-14-27(28)26-12-3-1-4-13-26/h1,3-6,12-15,29H,2,7-11,16-25H2/t29-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	376	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5HT6 receptor expressed in HEK293 cells after 1 hr				Eur J Med Chem 92: 202-11 (2015) Article DOI: 10.1016/j.ejmech.2014.12.041 BindingDB Entry DOI: 10.7270/Q2TT4SNW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50070615 (CHEMBL3409039) Show SMILES O=C(CCCCN1CCN(CC1)c1ccccc1-c1ccccc1)N1CCC[C@H]1C(=O)N1CCCCC1 |r| Show InChI InChI=1S/C31H42N4O2/c36-30(35-21-11-16-29(35)31(37)34-19-8-2-9-20-34)17-7-10-18-32-22-24-33(25-23-32)28-15-6-5-14-27(28)26-12-3-1-4-13-26/h1,3-6,12-15,29H,2,7-11,16-25H2/t29-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.68E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-ketanserin from human 5HT2A receptor expressed in HEK293 cells after 1 hrs				Eur J Med Chem 92: 202-11 (2015) Article DOI: 10.1016/j.ejmech.2014.12.041 BindingDB Entry DOI: 10.7270/Q2TT4SNW
					More data for this Ligand-Target Pair