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SMILES: CC[C@H](C)[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCCN)NC(=O)c1cc(O)ccc1O)C(=O)N[C@@H](CC)C(O)=O

InChI Key: InChIKey=FIWBRHJOEVKTAF-BEVGNBANSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50070695   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prothrombin


(Homo sapiens (Human))		BDBM50070695
PNG
(CHEMBL2372716 | Nazumamide A (NAZA) analogue)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCCN)NC(=O)c1cc(O)ccc1O)C(=O)N[C@@H](CC)C(O)=O
Show InChI InChI=1S/C34H46N6O8/c1-4-19(3)29(33(46)37-24(5-2)34(47)48)40-32(45)27(16-20-18-36-25-11-7-6-10-22(20)25)39-31(44)26(12-8-9-15-35)38-30(43)23-17-21(41)13-14-28(23)42/h6-7,10-11,13-14,17-19,24,26-27,29,36,41-42H,4-5,8-9,12,15-16,35H2,1-3H3,(H,37,46)(H,38,43)(H,39,44)(H,40,45)(H,47,48)/t19?,24?,26-,27-,29-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 1.69E+5n/an/an/an/a8.3n/a



Central Drug Research Institute

Curated by ChEMBL


Assay Description
Anti-thrombin activity by competitive enzyme assay using the fluorogenic substrate Tos-Gly-Pro-Arg-AMC at pH 8.3.

Bioorg Med Chem Lett 8: 1669-72 (1999)


BindingDB Entry DOI: 10.7270/Q2G73CV8
More data for this
Ligand-Target Pair