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SMILES: CC(=O)O[C@H]1CC[C@@]2(C)[C@@H](CC[C@]3(C)Oc4c5COC(=O)c5cc(O)c4C[C@H]23)C1(C)C

InChI Key: InChIKey=BOVRDZLKBBUXQQ-BOWIAGTOSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50071241   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha


(Homo sapiens (Human))		BDBM50071241
PNG
(Acetic acid (6aR,6bS,9S,10aR,12aS)-5-hydroxy-6b,10...)
Show SMILES CC(=O)O[C@H]1CC[C@@]2(C)[C@@H](CC[C@]3(C)Oc4c5COC(=O)c5cc(O)c4C[C@H]23)C1(C)C
Show InChI InChI=1S/C25H32O6/c1-13(26)30-20-7-8-24(4)18(23(20,2)3)6-9-25(5)19(24)11-15-17(27)10-14-16(21(15)31-25)12-29-22(14)28/h10,18-20,27H,6-9,11-12H2,1-5H3/t18-,19+,20-,24-,25-/m0/s1
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PubMed
n/an/a 1.30E+4n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human recombinant farnesyltransferase

Bioorg Med Chem Lett 8: 2071-6 (1999)


BindingDB Entry DOI: 10.7270/Q2W958BG
More data for this
Ligand-Target Pair