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SMILES: NC(=NCc1ccc(cc1)C(F)(F)F)c1ccc(Cc2cnc[nH]2)cc1

InChI Key: InChIKey=JXOKPIBNLUZFEA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50071494   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(GUINEA PIG)		BDBM50071494
PNG
(4-(1H-Imidazol-4-ylmethyl)-N-(4-trifluoromethyl-be...)
Show SMILES NC(=NCc1ccc(cc1)C(F)(F)F)c1ccc(Cc2cnc[nH]2)cc1 |w:2.2|
Show InChI InChI=1S/C19H17F3N4/c20-19(21,22)16-7-3-14(4-8-16)10-25-18(23)15-5-1-13(2-6-15)9-17-11-24-12-26-17/h1-8,11-12H,9-10H2,(H2,23,25)(H,24,26)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Patents
PubMed
 140n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Inhibition of N-alpha-methylhistamine binding to histamine H3 receptor of guinea pig brain membranes

Bioorg Med Chem Lett 8: 2263-8 (1999)


BindingDB Entry DOI: 10.7270/Q2TD9WH3
More data for this
Ligand-Target Pair