BDBM50071916 4-[2,5-Bis-(4-fluoro-phenyl)-1H-pyrrol-3-yl]-pyridine::CHEMBL91648

SMILES: Fc1ccc(cc1)-c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1

InChI Key: InChIKey=CSXBVJCIVUUQNW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50071916   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase p38 alpha (Rattus norvegicus)	BDBM50071916 (4-[2,5-Bis-(4-fluoro-phenyl)-1H-pyrrol-3-yl]-pyrid...) Show SMILES Fc1ccc(cc1)-c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C21H14F2N2/c22-17-5-1-15(2-6-17)20-13-19(14-9-11-24-12-10-14)21(25-20)16-3-7-18(23)8-4-16/h1-13,25H	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibitory potency evaluated against rat p38 kinase				Bioorg Med Chem Lett 8: 2689-94 (1999) BindingDB Entry DOI: 10.7270/Q27D2T9N
					More data for this Ligand-Target Pair