BDBM50072061 3-(4-Methanesulfonyl-phenyl)-2-phenyl-pyridine::CHEMBL96842

SMILES: CS(=O)(=O)c1ccc(cc1)-c1cccnc1-c1ccccc1

InChI Key: InChIKey=VDLKSALFSXAOKW-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50072061   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E synthase/G/H synthase 2 (Homo sapiens (Human))	BDBM50072061 (3-(4-Methanesulfonyl-phenyl)-2-phenyl-pyridine | C...) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cccnc1-c1ccccc1 Show InChI InChI=1S/C18H15NO2S/c1-22(20,21)16-11-9-14(10-12-16)17-8-5-13-19-18(17)15-6-3-2-4-7-15/h2-13H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of PGE-2 produced by arachidonic acid-stimulated CHO cells stably expressing human Prostaglandin G/H synthase 2				Bioorg Med Chem Lett 8: 2777-82 (1999) BindingDB Entry DOI: 10.7270/Q2FX78M0
					More data for this Ligand-Target Pair
Cyclooxygenase-1 (COX-1) (Homo sapiens (Human))	BDBM50072061 (3-(4-Methanesulfonyl-phenyl)-2-phenyl-pyridine | C...) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cccnc1-c1ccccc1 Show InChI InChI=1S/C18H15NO2S/c1-22(20,21)16-11-9-14(10-12-16)17-8-5-13-19-18(17)15-6-3-2-4-7-15/h2-13H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of Prostaglandin G/H synthase 1 was measured by the inhibition of PGE-2 produced by microsomes from U937 cells at subsaturating arachidoni...				Bioorg Med Chem Lett 8: 2777-82 (1999) BindingDB Entry DOI: 10.7270/Q2FX78M0
					More data for this Ligand-Target Pair
Cyclooxygenase (Homo sapiens (Human))	BDBM50072061 (3-(4-Methanesulfonyl-phenyl)-2-phenyl-pyridine | C...) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cccnc1-c1ccccc1 Show InChI InChI=1S/C18H15NO2S/c1-22(20,21)16-11-9-14(10-12-16)17-8-5-13-19-18(17)15-6-3-2-4-7-15/h2-13H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
The DuPont Pharmaceutical Company Curated by ChEMBL					Assay Description In vitro inhibitory concentration against recombinant human Prostaglandin G/H synthase 2 obtained from baculovirus				Bioorg Med Chem Lett 9: 919-24 (1999) BindingDB Entry DOI: 10.7270/Q2QJ7GGC
					More data for this Ligand-Target Pair
Cyclooxygenase (Homo sapiens (Human))	BDBM50072061 (3-(4-Methanesulfonyl-phenyl)-2-phenyl-pyridine | C...) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cccnc1-c1ccccc1 Show InChI InChI=1S/C18H15NO2S/c1-22(20,21)16-11-9-14(10-12-16)17-8-5-13-19-18(17)15-6-3-2-4-7-15/h2-13H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of Prostaglandin G/H synthase 2 was measured by the inhibition of PGE-2 produced by lipopolysaccharide-challenged HWB				Bioorg Med Chem Lett 8: 2777-82 (1999) BindingDB Entry DOI: 10.7270/Q2FX78M0
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase) (Ovis aries (Sheep))	BDBM50072061 (3-(4-Methanesulfonyl-phenyl)-2-phenyl-pyridine | C...) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cccnc1-c1ccccc1 Show InChI InChI=1S/C18H15NO2S/c1-22(20,21)16-11-9-14(10-12-16)17-8-5-13-19-18(17)15-6-3-2-4-7-15/h2-13H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
The DuPont Pharmaceutical Company Curated by ChEMBL					Assay Description In vitro inhibitory concentration against ovine COX-1				Bioorg Med Chem Lett 9: 919-24 (1999) BindingDB Entry DOI: 10.7270/Q2QJ7GGC
					More data for this Ligand-Target Pair