BDBM50072062 3-(4-Methanesulfonyl-phenyl)-[2,3']bipyridinyl::CHEMBL329419

SMILES: CS(=O)(=O)c1ccc(cc1)-c1cccnc1-c1cccnc1

InChI Key: InChIKey=UKAQGBBFNWGTGJ-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50072062   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E synthase/G/H synthase 2 (Homo sapiens (Human))	BDBM50072062 (3-(4-Methanesulfonyl-phenyl)-[2,3']bipyridinyl | C...) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cccnc1-c1cccnc1 Show InChI InChI=1S/C17H14N2O2S/c1-22(20,21)15-8-6-13(7-9-15)16-5-3-11-19-17(16)14-4-2-10-18-12-14/h2-12H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of Prostaglandin G/H synthase 2 was measured by the inhibition of PGE-2 produced by lipopolysaccharide-challenged HWB				Bioorg Med Chem Lett 8: 2777-82 (1999) BindingDB Entry DOI: 10.7270/Q2FX78M0
					More data for this Ligand-Target Pair
Cyclooxygenase (Homo sapiens (Human))	BDBM50072062 (3-(4-Methanesulfonyl-phenyl)-[2,3']bipyridinyl | C...) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cccnc1-c1cccnc1 Show InChI InChI=1S/C17H14N2O2S/c1-22(20,21)15-8-6-13(7-9-15)16-5-3-11-19-17(16)14-4-2-10-18-12-14/h2-12H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of PGE-2 produced by arachidonic acid-stimulated CHO cells stably expressing human Prostaglandin G/H synthase 2				Bioorg Med Chem Lett 8: 2777-82 (1999) BindingDB Entry DOI: 10.7270/Q2FX78M0
					More data for this Ligand-Target Pair
Cyclooxygenase-1 (COX-1) (Homo sapiens (Human))	BDBM50072062 (3-(4-Methanesulfonyl-phenyl)-[2,3']bipyridinyl | C...) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cccnc1-c1cccnc1 Show InChI InChI=1S/C17H14N2O2S/c1-22(20,21)15-8-6-13(7-9-15)16-5-3-11-19-17(16)14-4-2-10-18-12-14/h2-12H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of Prostaglandin G/H synthase 1 was measured by the inhibition of PGE-2 produced by microsomes from U937 cells at subsaturating arachidoni...				Bioorg Med Chem Lett 8: 2777-82 (1999) BindingDB Entry DOI: 10.7270/Q2FX78M0
					More data for this Ligand-Target Pair