BDBM50072242 4-(3,4-Dichloro-phenyl)-2-hydroxy-4-oxo-butyric acid::CHEMBL99339
SMILES: OC(CC(=O)c1ccc(Cl)c(Cl)c1)C(O)=O
InChI Key: InChIKey=OFKDXERWJCPSAE-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kynurenine 3-monooxygenase (Homo sapiens (Human)) | BDBM50072242 (4-(3,4-Dichloro-phenyl)-2-hydroxy-4-oxo-butyric ac...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia& Upjohn Curated by ChEMBL | Assay Description Compound was evaluated for inhibition of human recombinant KYN 3-OHase | Bioorg Med Chem Lett 8: 2907-12 (1999) BindingDB Entry DOI: 10.7270/Q23X874K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kynurenine 3-monooxygenase (Rattus norvegicus) | BDBM50072242 (4-(3,4-Dichloro-phenyl)-2-hydroxy-4-oxo-butyric ac...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia& Upjohn Curated by ChEMBL | Assay Description Compound was evaluated for inhibition of rat brain KYN 3-OHase | Bioorg Med Chem Lett 8: 2907-12 (1999) BindingDB Entry DOI: 10.7270/Q23X874K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kynurenine 3-monooxygenase (Rattus norvegicus) | BDBM50072242 (4-(3,4-Dichloro-phenyl)-2-hydroxy-4-oxo-butyric ac...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia& Upjohn Curated by ChEMBL | Assay Description Compound was evaluated for inhibition of rat liver KYN 3-OHase | Bioorg Med Chem Lett 8: 2907-12 (1999) BindingDB Entry DOI: 10.7270/Q23X874K | |||||||||||
More data for this Ligand-Target Pair |