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SMILES: [O-]P([O-])(=O)OC(F)(F)c1ccc2ccccc2c1

InChI Key: InChIKey=PZTXDSDEUMYUMI-UHFFFAOYSA-L

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50072597   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein phosphatase non-receptor type 1


(Homo sapiens (Human))		BDBM50072597
PNG
((Difluoro-naphthalen-2-yl-methyl)-phosphonium | CH...)
Show SMILES [O-]P([O-])(=O)OC(F)(F)c1ccc2ccccc2c1
Show InChI InChI=1S/C11H9F2O4P/c12-11(13,17-18(14,15)16)10-6-5-8-3-1-2-4-9(8)7-10/h1-7H,(H2,14,15,16)/p-2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

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PC cid
PC sid
UniChem
PubMed
n/an/a 3.50E+4n/an/an/an/an/an/a



University of Toronto

Curated by ChEMBL


Assay Description
Inhibitory activity against protein tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate as substrate at Km concentration (20 uM)

Bioorg Med Chem Lett 8: 3275-80 (1999)


BindingDB Entry DOI: 10.7270/Q20R9NK3
More data for this
Ligand-Target Pair