BDBM50075165 (E)-3-(3,5-Dimethoxy-phenyl)-N-[(S)-1-(5-methyl-4-oxo-4H-thieno[2,3-d][1,3]oxazin-2-yl)-ethyl]-acrylamide::CHEMBL138589

SMILES: COc1cc(OC)cc(\C=C\C(=O)N[C@@H](C)c2nc3scc(C)c3c(=O)o2)c1

InChI Key: InChIKey=BKVLMKNIYFDHLX-FYJFLYSWSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50075165   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human herpesvirus 4 protease/capsid scaffold protein (Epstein-Barr virus (strain B95-8) (HHV-4) (Human h...)	BDBM50075165 ((E)-3-(3,5-Dimethoxy-phenyl)-N-[(S)-1-(5-methyl-4-...) Show SMILES COc1cc(OC)cc(\C=C\C(=O)N[C@@H](C)c2nc3scc(C)c3c(=O)o2)c1 Show InChI InChI=1S/C20H20N2O5S/c1-11-10-28-19-17(11)20(24)27-18(22-19)12(2)21-16(23)6-5-13-7-14(25-3)9-15(8-13)26-4/h5-10,12H,1-4H3,(H,21,23)/b6-5+/t12-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against cytomegalovirus (CMV) protease was determined using quenched fluorescence assay				Bioorg Med Chem Lett 9: 443-8 (1999) BindingDB Entry DOI: 10.7270/Q2ZC822V
					More data for this Ligand-Target Pair
Human herpesvirus 2 protease (Human herpesvirus 2 (strain HG52) (HHV-2) (Human h...)	BDBM50075165 ((E)-3-(3,5-Dimethoxy-phenyl)-N-[(S)-1-(5-methyl-4-...) Show SMILES COc1cc(OC)cc(\C=C\C(=O)N[C@@H](C)c2nc3scc(C)c3c(=O)o2)c1 Show InChI InChI=1S/C20H20N2O5S/c1-11-10-28-19-17(11)20(24)27-18(22-19)12(2)21-16(23)6-5-13-7-14(25-3)9-15(8-13)26-4/h5-10,12H,1-4H3,(H,21,23)/b6-5+/t12-/m0/s1	MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against herpes simplex virus type 2 (HSV-2) protease was determined using quenched fluorescence assay				Bioorg Med Chem Lett 9: 443-8 (1999) BindingDB Entry DOI: 10.7270/Q2ZC822V
					More data for this Ligand-Target Pair
Human herpesvirus 6 protease (Human herpesvirus 6A (strain Uganda-1102) (HHV-6 v...)	BDBM50075165 ((E)-3-(3,5-Dimethoxy-phenyl)-N-[(S)-1-(5-methyl-4-...) Show SMILES COc1cc(OC)cc(\C=C\C(=O)N[C@@H](C)c2nc3scc(C)c3c(=O)o2)c1 Show InChI InChI=1S/C20H20N2O5S/c1-11-10-28-19-17(11)20(24)27-18(22-19)12(2)21-16(23)6-5-13-7-14(25-3)9-15(8-13)26-4/h5-10,12H,1-4H3,(H,21,23)/b6-5+/t12-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against Varicella Zoster Virus (VZV) protease was determined using quenched fluorescence assay				Bioorg Med Chem Lett 9: 443-8 (1999) BindingDB Entry DOI: 10.7270/Q2ZC822V
					More data for this Ligand-Target Pair