BDBM50075171 (E)-4-Oxo-4-thiophen-2-yl-but-2-enoic acid [(S)-1-(5-methyl-4-oxo-4H-thieno[2,3-d][1,3]oxazin-2-yl)-ethyl]-amide::CHEMBL335147

SMILES: C[C@H](NC(=O)\C=C\C(=O)c1cccs1)c1nc2scc(C)c2c(=O)o1

InChI Key: InChIKey=CIGRRSYBWWHXPH-PORFMDCZSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50075171   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human rhinovirus A protease (Human rhinovirus B)	BDBM50075171 ((E)-4-Oxo-4-thiophen-2-yl-but-2-enoic acid [(S)-1-...) Show SMILES C[C@H](NC(=O)\C=C\C(=O)c1cccs1)c1nc2scc(C)c2c(=O)o1 Show InChI InChI=1S/C17H14N2O4S2/c1-9-8-25-16-14(9)17(22)23-15(19-16)10(2)18-13(21)6-5-11(20)12-4-3-7-24-12/h3-8,10H,1-2H3,(H,18,21)/b6-5+/t10-/m0/s1	MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity of the compound against varicella zoster virus (VZV) protease				Bioorg Med Chem Lett 9: 449-52 (1999) BindingDB Entry DOI: 10.7270/Q2TM799P
					More data for this Ligand-Target Pair
Human herpesvirus 2 protease (Human herpesvirus 2 (strain HG52) (HHV-2) (Human h...)	BDBM50075171 ((E)-4-Oxo-4-thiophen-2-yl-but-2-enoic acid [(S)-1-...) Show SMILES C[C@H](NC(=O)\C=C\C(=O)c1cccs1)c1nc2scc(C)c2c(=O)o1 Show InChI InChI=1S/C17H14N2O4S2/c1-9-8-25-16-14(9)17(22)23-15(19-16)10(2)18-13(21)6-5-11(20)12-4-3-7-24-12/h3-8,10H,1-2H3,(H,18,21)/b6-5+/t10-/m0/s1	MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against herpes simplex virus protease (HSV-2)				Bioorg Med Chem Lett 9: 449-52 (1999) BindingDB Entry DOI: 10.7270/Q2TM799P
					More data for this Ligand-Target Pair
Human herpes virus 5 capsid protein P40 (Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)	BDBM50075171 ((E)-4-Oxo-4-thiophen-2-yl-but-2-enoic acid [(S)-1-...) Show SMILES C[C@H](NC(=O)\C=C\C(=O)c1cccs1)c1nc2scc(C)c2c(=O)o1 Show InChI InChI=1S/C17H14N2O4S2/c1-9-8-25-16-14(9)17(22)23-15(19-16)10(2)18-13(21)6-5-11(20)12-4-3-7-24-12/h3-8,10H,1-2H3,(H,18,21)/b6-5+/t10-/m0/s1	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against cytomegalovirus protease (CMV)				Bioorg Med Chem Lett 9: 449-52 (1999) BindingDB Entry DOI: 10.7270/Q2TM799P
					More data for this Ligand-Target Pair