null

SMILES: CC[C@H]1Nc2cc3[nH]c(=O)cc(c3cc2CC1(CC)CC)C(F)(F)F

InChI Key: InChIKey=XBVYEKYLTSWRCK-MRXNPFEDSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50076718   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen receptor (Homo sapiens (Human))	BDBM50076718 ((R)-7,7,8-Triethyl-4-trifluoromethyl-6,7,8,9-tetra...) Show SMILES CC[C@H]1Nc2cc3[nH]c(=O)cc(c3cc2CC1(CC)CC)C(F)(F)F Show InChI InChI=1S/C19H23F3N2O/c1-4-16-18(5-2,6-3)10-11-7-12-13(19(20,21)22)8-17(25)24-15(12)9-14(11)23-16/h7-9,16,23H,4-6,10H2,1-3H3,(H,24,25)/t16-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Binding affinity towards human androgen receptor (hAR), using dihydrotestosterone as radioligand for competitive binding assay				Bioorg Med Chem Lett 9: 1009-12 (1999) BindingDB Entry DOI: 10.7270/Q2F18XWV
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50076718 ((R)-7,7,8-Triethyl-4-trifluoromethyl-6,7,8,9-tetra...) Show SMILES CC[C@H]1Nc2cc3[nH]c(=O)cc(c3cc2CC1(CC)CC)C(F)(F)F Show InChI InChI=1S/C19H23F3N2O/c1-4-16-18(5-2,6-3)10-11-7-12-13(19(20,21)22)8-17(25)24-15(12)9-14(11)23-16/h7-9,16,23H,4-6,10H2,1-3H3,(H,24,25)/t16-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Antagonistic activity against human androgen receptor (hAR) expressed in CV-1 cell lines				Bioorg Med Chem Lett 9: 1009-12 (1999) BindingDB Entry DOI: 10.7270/Q2F18XWV
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50076718 ((R)-7,7,8-Triethyl-4-trifluoromethyl-6,7,8,9-tetra...) Show SMILES CC[C@H]1Nc2cc3[nH]c(=O)cc(c3cc2CC1(CC)CC)C(F)(F)F Show InChI InChI=1S/C19H23F3N2O/c1-4-16-18(5-2,6-3)10-11-7-12-13(19(20,21)22)8-17(25)24-15(12)9-14(11)23-16/h7-9,16,23H,4-6,10H2,1-3H3,(H,24,25)/t16-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Antagonistic activity against human androgen receptor (hAR) expressed in CV-1 cell lines				Bioorg Med Chem Lett 9: 1009-12 (1999) BindingDB Entry DOI: 10.7270/Q2F18XWV
					More data for this Ligand-Target Pair