BDBM50076723 (S)-5-(3-Amino-4-methylamino-phenyl)-2-(naphthalene-2-sulfonylamino)-pent-4-ynoic acid cyclopentyl-methyl-amide::CHEMBL7124
SMILES: CNc1ccc(cc1N)C#CC[C@H](NS(=O)(=O)c1ccc2ccccc2c1)C(=O)N(C)C1CCCC1
InChI Key: InChIKey=GANBKJDEISWUIT-MHZLTWQESA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prothrombin (Homo sapiens (Human)) | BDBM50076723 ((S)-5-(3-Amino-4-methylamino-phenyl)-2-(naphthalen...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Biotech Research Institute Curated by ChEMBL | Assay Description Inhibition of human thrombin | Bioorg Med Chem Lett 9: 1013-8 (1999) BindingDB Entry DOI: 10.7270/Q298866C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypsin (Bos taurus (bovine)) | BDBM50076723 ((S)-5-(3-Amino-4-methylamino-phenyl)-2-(naphthalen...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Biotech Research Institute Curated by ChEMBL | Assay Description Inhibitory activity of the compound against bovine trypsin | Bioorg Med Chem Lett 9: 1013-8 (1999) BindingDB Entry DOI: 10.7270/Q298866C | |||||||||||
More data for this Ligand-Target Pair |