BDBM50077174 6-[6-(3-Carbamimidoyl-phenoxy)-5-oxo-1,2,5,6-tetrahydro-pyrazin-2-yloxy]-pyridine-2-carboxamidine::CHEMBL50961

SMILES: NC(=N)c1cccc(OC2N=C(CNC2=O)Oc2cccc(n2)C(N)=N)c1

InChI Key: InChIKey=PWTAVJTYNIFGIS-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50077174   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50077174 (6-[6-(3-Carbamimidoyl-phenoxy)-5-oxo-1,2,5,6-tetra...) Show SMILES NC(=N)c1cccc(OC2N=C(CNC2=O)Oc2cccc(n2)C(N)=N)c1 |c:10| Show InChI InChI=1S/C17H17N7O3/c18-14(19)9-3-1-4-10(7-9)26-17-16(25)22-8-13(24-17)27-12-6-2-5-11(23-12)15(20)21/h1-7,17H,8H2,(H3,18,19)(H3,20,21)(H,22,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences Curated by ChEMBL					Assay Description Compound was tested for inhibition activity against Coagulation factor X				J Med Chem 42: 1749-56 (1999) Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF
					More data for this Ligand-Target Pair
Serine protease 1 (Bos taurus (bovine))	BDBM50077174 (6-[6-(3-Carbamimidoyl-phenoxy)-5-oxo-1,2,5,6-tetra...) Show SMILES NC(=N)c1cccc(OC2N=C(CNC2=O)Oc2cccc(n2)C(N)=N)c1 |c:10| Show InChI InChI=1S/C17H17N7O3/c18-14(19)9-3-1-4-10(7-9)26-17-16(25)22-8-13(24-17)27-12-6-2-5-11(23-12)15(20)21/h1-7,17H,8H2,(H3,18,19)(H3,20,21)(H,22,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	760	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences Curated by ChEMBL					Assay Description Compound was tested for inhibition activity against bovine trypsin.				J Med Chem 42: 1749-56 (1999) Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50077174 (6-[6-(3-Carbamimidoyl-phenoxy)-5-oxo-1,2,5,6-tetra...) Show SMILES NC(=N)c1cccc(OC2N=C(CNC2=O)Oc2cccc(n2)C(N)=N)c1 |c:10| Show InChI InChI=1S/C17H17N7O3/c18-14(19)9-3-1-4-10(7-9)26-17-16(25)22-8-13(24-17)27-12-6-2-5-11(23-12)15(20)21/h1-7,17H,8H2,(H3,18,19)(H3,20,21)(H,22,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences Curated by ChEMBL					Assay Description Compound was tested for inhibition activity against human thrombin (FIIa)				J Med Chem 42: 1749-56 (1999) Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF
					More data for this Ligand-Target Pair