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SMILES: Clc1ccc(OCCN2CCc3ccccc3CC2)c2CC(=O)Nc12

InChI Key: InChIKey=DZAIXMOGMCWKEV-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50077574   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50077574 (7-Chloro-4-[2-(1,2,4,5-tetrahydro-benzo[d]azepin-3...) Show SMILES Clc1ccc(OCCN2CCc3ccccc3CC2)c2CC(=O)Nc12 Show InChI InChI=1S/C20H21ClN2O2/c21-17-5-6-18(16-13-19(24)22-20(16)17)25-12-11-23-9-7-14-3-1-2-4-15(14)8-10-23/h1-6H,7-13H2,(H,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.550	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Laboratories Curated by ChEMBL					Assay Description In vitro high binding affinity towards Dopamine receptor D2 by the displacement of [3H]-quinpirole radioligand in rat striatal membranes				J Med Chem 42: 2007-20 (1999) Article DOI: 10.1021/jm990023s BindingDB Entry DOI: 10.7270/Q25D8R1W
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50077574 (7-Chloro-4-[2-(1,2,4,5-tetrahydro-benzo[d]azepin-3...) Show SMILES Clc1ccc(OCCN2CCc3ccccc3CC2)c2CC(=O)Nc12 Show InChI InChI=1S/C20H21ClN2O2/c21-17-5-6-18(16-13-19(24)22-20(16)17)25-12-11-23-9-7-14-3-1-2-4-15(14)8-10-23/h1-6H,7-13H2,(H,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Laboratories Curated by ChEMBL					Assay Description In vitro low binding affinity towards Dopamine receptor D2 by the displacement of [3H]-spiperone radioligand in rat striatal membranes				J Med Chem 42: 2007-20 (1999) Article DOI: 10.1021/jm990023s BindingDB Entry DOI: 10.7270/Q25D8R1W
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50077574 (7-Chloro-4-[2-(1,2,4,5-tetrahydro-benzo[d]azepin-3...) Show SMILES Clc1ccc(OCCN2CCc3ccccc3CC2)c2CC(=O)Nc12 Show InChI InChI=1S/C20H21ClN2O2/c21-17-5-6-18(16-13-19(24)22-20(16)17)25-12-11-23-9-7-14-3-1-2-4-15(14)8-10-23/h1-6H,7-13H2,(H,22,24)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]-8-OH-DPAT radioligand in rat hippocampal homogenates				J Med Chem 42: 2007-20 (1999) Article DOI: 10.1021/jm990023s BindingDB Entry DOI: 10.7270/Q25D8R1W
					More data for this Ligand-Target Pair