BDBM50077887 CHEMBL3417059::US9611229, 17
SMILES: Fc1ccc(Cn2cc(NCCN3CCCCC3)nn2)cc1
InChI Key: InChIKey=VJTNUVXGKSYZBJ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse)) | BDBM50077887 (CHEMBL3417059 | US9611229, 17) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | US Patent | 51.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
LABORATORIOS DEL DR. ESTEVE S.A. US Patent | Assay Description Brain membrane preparation and binding assays for the 61-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y. For... | US Patent US9611229 (2017) BindingDB Entry DOI: 10.7270/Q2T155QS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50077887 (CHEMBL3417059 | US9611229, 17) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 52 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Esteve Curated by ChEMBL | Assay Description Displacement of [3H](+)-pentazocine from human sigma 1 receptor transfected in HEK293 cells after 120 mins by liquid scintillation counting | J Med Chem 58: 2441-51 (2015) Article DOI: 10.1021/jm501920g BindingDB Entry DOI: 10.7270/Q29C704N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50077887 (CHEMBL3417059 | US9611229, 17) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Esteve Curated by ChEMBL | Assay Description Inhibition of human ERG expressed in CHO cells at -80 mV holding potential by whole cell patch clamp assay | J Med Chem 58: 2441-51 (2015) Article DOI: 10.1021/jm501920g BindingDB Entry DOI: 10.7270/Q29C704N | |||||||||||
More data for this Ligand-Target Pair |