BDBM50077905 CHEMBL3417068::US9611229, 33
SMILES: Clc1ccc(Cn2cc(NCCN3CCCOCC3)nn2)cc1Cl
InChI Key: InChIKey=JIZCRDLCYFMDNS-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50077905 (CHEMBL3417068 | US9611229, 33) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Esteve Curated by ChEMBL | Assay Description Displacement of [3H](+)-pentazocine from human sigma 1 receptor transfected in HEK293 cells after 120 mins by liquid scintillation counting | J Med Chem 58: 2441-51 (2015) Article DOI: 10.1021/jm501920g BindingDB Entry DOI: 10.7270/Q29C704N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse)) | BDBM50077905 (CHEMBL3417068 | US9611229, 33) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | US Patent | 13.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
LABORATORIOS DEL DR. ESTEVE S.A. US Patent | Assay Description Brain membrane preparation and binding assays for the 61-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y. For... | US Patent US9611229 (2017) BindingDB Entry DOI: 10.7270/Q2T155QS | |||||||||||
More data for this Ligand-Target Pair |