BDBM50077963 4-(2,5-Diphenyl-3H-imidazol-4-yl)-pyridine::CHEMBL69228

SMILES: c1ccc(cc1)-c1nc(c([nH]1)-c1ccccc1)-c1ccncc1

InChI Key: InChIKey=YYQUGNLGTLHJFO-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50077963   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50077963 (4-(2,5-Diphenyl-3H-imidazol-4-yl)-pyridine | CHEMB...) Show SMILES c1ccc(cc1)-c1nc(c([nH]1)-c1ccccc1)-c1ccncc1 Show InChI InChI=1S/C20H15N3/c1-3-7-15(8-4-1)18-19(16-11-13-21-14-12-16)23-20(22-18)17-9-5-2-6-10-17/h1-14H,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human RAF proto-oncogene serine/threonine-protein kinase				J Med Chem 42: 2180-90 (1999) Article DOI: 10.1021/jm9805236 BindingDB Entry DOI: 10.7270/Q2Q81C8D
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 9 (Homo sapiens (Human))	BDBM50077963 (4-(2,5-Diphenyl-3H-imidazol-4-yl)-pyridine | CHEMB...) Show SMILES c1ccc(cc1)-c1nc(c([nH]1)-c1ccccc1)-c1ccncc1 Show InChI InChI=1S/C20H15N3/c1-3-7-15(8-4-1)18-19(16-11-13-21-14-12-16)23-20(22-18)17-9-5-2-6-10-17/h1-14H,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of c-Jun N-terminal kinase 2-alpha 1				J Med Chem 42: 2180-90 (1999) Article DOI: 10.1021/jm9805236 BindingDB Entry DOI: 10.7270/Q2Q81C8D
					More data for this Ligand-Target Pair