BDBM50079319 3-Ethyl-2-oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid [2-(4-ethyl-piperazin-1-yl)-ethyl]-amide::CHEMBL318764

SMILES: CCN1CCN(CCNC(=O)n2c3ccccc3n(CC)c2=O)CC1

InChI Key: InChIKey=IQSOHLHKGXVDTJ-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50079319   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
HTR4 (GUINEA PIG)	BDBM50079319 (3-Ethyl-2-oxo-2,3-dihydro-benzoimidazole-1-carboxy...) Show SMILES CCN1CCN(CCNC(=O)n2c3ccccc3n(CC)c2=O)CC1 Show InChI InChI=1S/C18H27N5O2/c1-3-20-11-13-21(14-12-20)10-9-19-17(24)23-16-8-6-5-7-15(16)22(4-2)18(23)25/h5-8H,3-4,9-14H2,1-2H3,(H,19,24)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
FAES, S.A. Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 4 receptor in guinea pig striatum using [3H]GR-113808 as radioligand				J Med Chem 42: 2870-80 (1999) Article DOI: 10.1021/jm981098j BindingDB Entry DOI: 10.7270/Q24X58GN
					More data for this Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT)	BDBM50079319 (3-Ethyl-2-oxo-2,3-dihydro-benzoimidazole-1-carboxy...) Show SMILES CCN1CCN(CCNC(=O)n2c3ccccc3n(CC)c2=O)CC1 Show InChI InChI=1S/C18H27N5O2/c1-3-20-11-13-21(14-12-20)10-9-19-17(24)23-16-8-6-5-7-15(16)22(4-2)18(23)25/h5-8H,3-4,9-14H2,1-2H3,(H,19,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
FAES, S.A. Curated by ChEMBL					Assay Description Inhibitory concentration against 5-hydroxytryptamine 3 receptor in rat enthorinal cortex using [3H]-LY 278584 as radioligand				J Med Chem 42: 2870-80 (1999) Article DOI: 10.1021/jm981098j BindingDB Entry DOI: 10.7270/Q24X58GN
					More data for this Ligand-Target Pair