BDBM50079964 (S)-2-[2-({(S)-3-Methyl-2-[2-(3-quinolin-2-ylmethyl-3H-imidazol-4-yl)-acetylamino]-pentyl}-naphthalen-1-ylmethyl-amino)-acetylamino]-4-methylsulfanyl-butyric acid::CHEMBL114990

SMILES: CCC(C)[C@@H](CN(CC(=O)N[C@@H](CCSC)C(O)=O)Cc1cccc2ccccc12)NC(=O)Cc1cncn1Cc1ccc2ccccc2n1

InChI Key: InChIKey=ROPVYNUGSZRGBD-APAWJXJHSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50079964   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Geranylgeranyl Transferase (GGTase-I) (Bos taurus (bovine))	BDBM50079964 ((S)-2-[2-({(S)-3-Methyl-2-[2-(3-quinolin-2-ylmethy...) Show SMILES CCC(C)[C@@H](CN(CC(=O)N[C@@H](CCSC)C(O)=O)Cc1cccc2ccccc12)NC(=O)Cc1cncn1Cc1ccc2ccccc2n1 Show InChI InChI=1S/C39H46N6O4S/c1-4-27(2)36(43-37(46)20-32-21-40-26-45(32)23-31-17-16-29-11-6-8-15-34(29)41-31)24-44(25-38(47)42-35(39(48)49)18-19-50-3)22-30-13-9-12-28-10-5-7-14-33(28)30/h5-17,21,26-27,35-36H,4,18-20,22-25H2,1-3H3,(H,42,47)(H,43,46)(H,48,49)/t27?,35-,36+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.75E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]GGPP incorporation into recombinant human Ha-RasCVLL by Geranylgeranyl transferase from bovine brain				J Med Chem 42: 3356-68 (1999) Article DOI: 10.1021/jm990080l BindingDB Entry DOI: 10.7270/Q27P9020
					More data for this Ligand-Target Pair
Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50079964 ((S)-2-[2-({(S)-3-Methyl-2-[2-(3-quinolin-2-ylmethy...) Show SMILES CCC(C)[C@@H](CN(CC(=O)N[C@@H](CCSC)C(O)=O)Cc1cccc2ccccc12)NC(=O)Cc1cncn1Cc1ccc2ccccc2n1 Show InChI InChI=1S/C39H46N6O4S/c1-4-27(2)36(43-37(46)20-32-21-40-26-45(32)23-31-17-16-29-11-6-8-15-34(29)41-31)24-44(25-38(47)42-35(39(48)49)18-19-50-3)22-30-13-9-12-28-10-5-7-14-33(28)30/h5-17,21,26-27,35-36H,4,18-20,22-25H2,1-3H3,(H,42,47)(H,43,46)(H,48,49)/t27?,35-,36+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by Farnesyltransferase				J Med Chem 42: 3356-68 (1999) Article DOI: 10.1021/jm990080l BindingDB Entry DOI: 10.7270/Q27P9020
					More data for this Ligand-Target Pair