BDBM50081962 (S)-3-Fluoromethyl-1,2,3,4-tetrahydro-isoquinoline::CHEMBL137607
SMILES: FC[C@@H]1Cc2ccccc2CN1
InChI Key: InChIKey=SLBKHMRNZGCZIO-JTQLQIEISA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Phenylethanolamine N-methyltransferase (Bos taurus (bovine)) | BDBM50081962![]() ((S)-3-Fluoromethyl-1,2,3,4-tetrahydro-isoquinoline...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 9.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas Curated by ChEMBL | Assay Description In vitro inhibition of PNMT (Phenylethanolamine N-Methyltransferase). | J Med Chem 42: 4351-61 (1999) BindingDB Entry DOI: 10.7270/Q2X0667W | |||||||||||
More data for this Ligand-Target Pair |