BDBM50081999 2-[4-(7-Fluoro-pyrrolo[1,2-a]quinoxalin-4-yl)-piperazin-1-yl]-ethanol::CHEMBL136449

SMILES: OCCN1CCN(CC1)c1nc2cc(F)ccc2n2cccc12

InChI Key: InChIKey=HNDUAMFNYJMLRR-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50081999   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT)	BDBM50081999 (2-[4-(7-Fluoro-pyrrolo[1,2-a]quinoxalin-4-yl)-pipe...) Show SMILES OCCN1CCN(CC1)c1nc2cc(F)ccc2n2cccc12 Show InChI InChI=1S/C17H19FN4O/c18-13-3-4-15-14(12-13)19-17(16-2-1-5-22(15)16)21-8-6-20(7-9-21)10-11-23/h1-5,12,23H,6-11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor from rat cortical homogenate using [3H]-zacopride as radioligand				J Med Chem 42: 4362-79 (1999) BindingDB Entry DOI: 10.7270/Q2S75FJM
					More data for this Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Homo sapiens (Human))	BDBM50081999 (2-[4-(7-Fluoro-pyrrolo[1,2-a]quinoxalin-4-yl)-pipe...) Show SMILES OCCN1CCN(CC1)c1nc2cc(F)ccc2n2cccc12 Show InChI InChI=1S/C17H19FN4O/c18-13-3-4-15-14(12-13)19-17(16-2-1-5-22(15)16)21-8-6-20(7-9-21)10-11-23/h1-5,12,23H,6-11H2	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	2.40	n/a	n/a	n/a	n/a
Universita' degli Studi di Salerno Curated by ChEMBL					Assay Description Effective concentration against 5-Hydroxytryptamine 3 receptor by measuring [14C]-guanidinium uptake on NG108-15 cells.				J Med Chem 42: 4362-79 (1999) BindingDB Entry DOI: 10.7270/Q2S75FJM
					More data for this Ligand-Target Pair