BDBM50083536 4-(3,4-Dichloro-phenyl)-1-methyl-piperidine-4-carboxylic acid ethyl ester::CHEMBL326243::CHEMBL541124

SMILES: CCOC(=O)C1(CCN(C)CC1)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=CVNBITYLPWBHNX-UHFFFAOYSA-N

Data: 9 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50083536   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50083536 (4-(3,4-Dichloro-phenyl)-1-methyl-piperidine-4-carb...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C15H19Cl2NO2/c1-3-20-14(19)15(6-8-18(2)9-7-15)11-4-5-12(16)13(17)10-11/h4-5,10H,3,6-9H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from serotonin transporter in Sprague-Dawley rat brain after 1 hr by liquid scintillation counting				Bioorg Med Chem 18: 8356-64 (2010) Article DOI: 10.1016/j.bmc.2010.09.060 BindingDB Entry DOI: 10.7270/Q2CN744P
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50083536 (4-(3,4-Dichloro-phenyl)-1-methyl-piperidine-4-carb...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C15H19Cl2NO2/c1-3-20-14(19)15(6-8-18(2)9-7-15)11-4-5-12(16)13(17)10-11/h4-5,10H,3,6-9H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]paroxetine binding to rat serotonin transporter				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50083536 (4-(3,4-Dichloro-phenyl)-1-methyl-piperidine-4-carb...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C15H19Cl2NO2/c1-3-20-14(19)15(6-8-18(2)9-7-15)11-4-5-12(16)13(17)10-11/h4-5,10H,3,6-9H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Displacement of [3H]-paroxetine from serotonin transporter (SERT)				Bioorg Med Chem Lett 9: 3273-6 (2000) BindingDB Entry DOI: 10.7270/Q23F4NVM
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50083536 (4-(3,4-Dichloro-phenyl)-1-methyl-piperidine-4-carb...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C15H19Cl2NO2/c1-3-20-14(19)15(6-8-18(2)9-7-15)11-4-5-12(16)13(17)10-11/h4-5,10H,3,6-9H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	125	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Displacement of [3H]-WIN- 35,428 from dopamine transporter (DAT)				Bioorg Med Chem Lett 9: 3273-6 (2000) BindingDB Entry DOI: 10.7270/Q23F4NVM
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50083536 (4-(3,4-Dichloro-phenyl)-1-methyl-piperidine-4-carb...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C15H19Cl2NO2/c1-3-20-14(19)15(6-8-18(2)9-7-15)11-4-5-12(16)13(17)10-11/h4-5,10H,3,6-9H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	125	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Displacement of [3H]WIN 35428 from dopamine transporter in Sprague-Dawley rat brain after 1 hr by liquid scintillation counting				Bioorg Med Chem 18: 8356-64 (2010) Article DOI: 10.1016/j.bmc.2010.09.060 BindingDB Entry DOI: 10.7270/Q2CN744P
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50083536 (4-(3,4-Dichloro-phenyl)-1-methyl-piperidine-4-carb...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C15H19Cl2NO2/c1-3-20-14(19)15(6-8-18(2)9-7-15)11-4-5-12(16)13(17)10-11/h4-5,10H,3,6-9H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	125	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]WIN-35428 binding to rat dopamine transporter				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50083536 (4-(3,4-Dichloro-phenyl)-1-methyl-piperidine-4-carb...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C15H19Cl2NO2/c1-3-20-14(19)15(6-8-18(2)9-7-15)11-4-5-12(16)13(17)10-11/h4-5,10H,3,6-9H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.04E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]DAMGO binding to mu-opioid receptor				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus (rat))	BDBM50083536 (4-(3,4-Dichloro-phenyl)-1-methyl-piperidine-4-carb...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C15H19Cl2NO2/c1-3-20-14(19)15(6-8-18(2)9-7-15)11-4-5-12(16)13(17)10-11/h4-5,10H,3,6-9H2,1-2H3	Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.82E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from norepinephrine transporter in Sprague-Dawley rat frontal cortex after 1 hr by liquid scintillation counting				Bioorg Med Chem 18: 8356-64 (2010) Article DOI: 10.1016/j.bmc.2010.09.060 BindingDB Entry DOI: 10.7270/Q2CN744P
					More data for this Ligand-Target Pair
Norepinephrine Monoamine transporters (Rattus norvegicus)	BDBM50083536 (4-(3,4-Dichloro-phenyl)-1-methyl-piperidine-4-carb...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C15H19Cl2NO2/c1-3-20-14(19)15(6-8-18(2)9-7-15)11-4-5-12(16)13(17)10-11/h4-5,10H,3,6-9H2,1-2H3	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.45E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]-nisoxetine binding to rat norepinephrine transporter				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
					More data for this Ligand-Target Pair