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SMILES: N[C@@H](CS)CNc1cccc(Oc2cccc(c2)C(O)=O)c1

InChI Key: InChIKey=PTYARAMVADWAJN-GFCCVEGCSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50083595   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50083595 (3-[3-((R)-2-Amino-3-mercapto-propylamino)-phenoxy]...) Show SMILES N[C@@H](CS)CNc1cccc(Oc2cccc(c2)C(O)=O)c1 Show InChI InChI=1S/C16H18N2O3S/c17-12(10-22)9-18-13-4-2-6-15(8-13)21-14-5-1-3-11(7-14)16(19)20/h1-8,12,18,22H,9-10,17H2,(H,19,20)/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.25	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of bovine Farnesyltransferase in vitro.				Bioorg Med Chem Lett 9: 3301-6 (2000) BindingDB Entry DOI: 10.7270/Q2Q52NT7
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50083595 (3-[3-((R)-2-Amino-3-mercapto-propylamino)-phenoxy]...) Show SMILES N[C@@H](CS)CNc1cccc(Oc2cccc(c2)C(O)=O)c1 Show InChI InChI=1S/C16H18N2O3S/c17-12(10-22)9-18-13-4-2-6-15(8-13)21-14-5-1-3-11(7-14)16(19)20/h1-8,12,18,22H,9-10,17H2,(H,19,20)/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ha-Ras by 50% in bovine brain at a concentration of ca. 1 ...				Bioorg Med Chem Lett 7: 1345-1348 (1997) Article DOI: 10.1016/S0960-894X(97)00225-4 BindingDB Entry DOI: 10.7270/Q28W3D96
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50083595 (3-[3-((R)-2-Amino-3-mercapto-propylamino)-phenoxy]...) Show SMILES N[C@@H](CS)CNc1cccc(Oc2cccc(c2)C(O)=O)c1 Show InChI InChI=1S/C16H18N2O3S/c17-12(10-22)9-18-13-4-2-6-15(8-13)21-14-5-1-3-11(7-14)16(19)20/h1-8,12,18,22H,9-10,17H2,(H,19,20)/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Geranylgeranyl transferase type I, an enzyme that recognizes CaaX sequences containing leucine as the terminal residue.				Bioorg Med Chem Lett 7: 1345-1348 (1997) Article DOI: 10.1016/S0960-894X(97)00225-4 BindingDB Entry DOI: 10.7270/Q28W3D96
					More data for this Ligand-Target Pair