null

SMILES: NS(=O)(=O)c1ccc(cc1)-c1coc(=O)n1-c1ccccc1Cl

InChI Key: InChIKey=XZBCHXZIDAPGAW-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50084342   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50084342 (4-[3-(2-Chloro-phenyl)-2-oxo-2,3-dihydro-oxazol-4-...) Show SMILES NS(=O)(=O)c1ccc(cc1)-c1coc(=O)n1-c1ccccc1Cl |(4.41,-9.17,;5.68,-10.06,;6.94,-10.95,;4.78,-11.33,;6.56,-8.8,;8.12,-8.92,;8.99,-7.64,;8.31,-6.26,;6.77,-6.14,;5.9,-7.4,;9.19,-5,;10.72,-5.02,;11.21,-3.6,;9.99,-2.67,;10.02,-1.13,;8.75,-3.53,;7.66,-2.43,;8.07,-.96,;6.98,.13,;5.49,-.28,;5.09,-1.73,;6.18,-2.83,;5.77,-4.32,)| Show InChI InChI=1S/C15H11ClN2O4S/c16-12-3-1-2-4-13(12)18-14(9-22-15(18)19)10-5-7-11(8-6-10)23(17,20)21/h1-9H,(H2,17,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibitory activity against prostaglandin G/H synthase 2				J Med Chem 43: 214-23 (2000) BindingDB Entry DOI: 10.7270/Q2DV1KK0
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50084342 (4-[3-(2-Chloro-phenyl)-2-oxo-2,3-dihydro-oxazol-4-...) Show SMILES NS(=O)(=O)c1ccc(cc1)-c1coc(=O)n1-c1ccccc1Cl |(4.41,-9.17,;5.68,-10.06,;6.94,-10.95,;4.78,-11.33,;6.56,-8.8,;8.12,-8.92,;8.99,-7.64,;8.31,-6.26,;6.77,-6.14,;5.9,-7.4,;9.19,-5,;10.72,-5.02,;11.21,-3.6,;9.99,-2.67,;10.02,-1.13,;8.75,-3.53,;7.66,-2.43,;8.07,-.96,;6.98,.13,;5.49,-.28,;5.09,-1.73,;6.18,-2.83,;5.77,-4.32,)| Show InChI InChI=1S/C15H11ClN2O4S/c16-12-3-1-2-4-13(12)18-14(9-22-15(18)19)10-5-7-11(8-6-10)23(17,20)21/h1-9H,(H2,17,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jadavpur University Curated by ChEMBL					Assay Description Binding affinity towards Prostaglandin G/H synthase 2				Bioorg Med Chem Lett 13: 3753-7 (2003) BindingDB Entry DOI: 10.7270/Q2JM2BS0
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50084342 (4-[3-(2-Chloro-phenyl)-2-oxo-2,3-dihydro-oxazol-4-...) Show SMILES NS(=O)(=O)c1ccc(cc1)-c1coc(=O)n1-c1ccccc1Cl |(4.41,-9.17,;5.68,-10.06,;6.94,-10.95,;4.78,-11.33,;6.56,-8.8,;8.12,-8.92,;8.99,-7.64,;8.31,-6.26,;6.77,-6.14,;5.9,-7.4,;9.19,-5,;10.72,-5.02,;11.21,-3.6,;9.99,-2.67,;10.02,-1.13,;8.75,-3.53,;7.66,-2.43,;8.07,-.96,;6.98,.13,;5.49,-.28,;5.09,-1.73,;6.18,-2.83,;5.77,-4.32,)| Show InChI InChI=1S/C15H11ClN2O4S/c16-12-3-1-2-4-13(12)18-14(9-22-15(18)19)10-5-7-11(8-6-10)23(17,20)21/h1-9H,(H2,17,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.54E+4	n/a	n/a	n/a	n/a	n/a	n/a
Jadavpur University Curated by ChEMBL					Assay Description Binding affinity towards Prostaglandin G/H synthase 1				Bioorg Med Chem Lett 13: 3753-7 (2003) BindingDB Entry DOI: 10.7270/Q2JM2BS0
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50084342 (4-[3-(2-Chloro-phenyl)-2-oxo-2,3-dihydro-oxazol-4-...) Show SMILES NS(=O)(=O)c1ccc(cc1)-c1coc(=O)n1-c1ccccc1Cl |(4.41,-9.17,;5.68,-10.06,;6.94,-10.95,;4.78,-11.33,;6.56,-8.8,;8.12,-8.92,;8.99,-7.64,;8.31,-6.26,;6.77,-6.14,;5.9,-7.4,;9.19,-5,;10.72,-5.02,;11.21,-3.6,;9.99,-2.67,;10.02,-1.13,;8.75,-3.53,;7.66,-2.43,;8.07,-.96,;6.98,.13,;5.49,-.28,;5.09,-1.73,;6.18,-2.83,;5.77,-4.32,)| Show InChI InChI=1S/C15H11ClN2O4S/c16-12-3-1-2-4-13(12)18-14(9-22-15(18)19)10-5-7-11(8-6-10)23(17,20)21/h1-9H,(H2,17,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.54E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibitory activity against prostaglandin G/H synthase 1				J Med Chem 43: 214-23 (2000) BindingDB Entry DOI: 10.7270/Q2DV1KK0
					More data for this Ligand-Target Pair